Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery
Advanced Healthcare Materials, EarlyView.Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang +6 more
wiley +1 more source
Tumor Microenvironment‐responsive Nanocatalyst for Targeted Chemodynamic Cancer Therapy
Advanced Healthcare Materials, EarlyView.An Tumor microenvironment‐responsive nanocatalyst system composed of PLGA‐encapsulated Ca–Fe peroxide and polyarginine enables sustainable Fenton reaction in tumors. Low levels of H2O2 (50–100 µm) initiate the nanoparticle degradation, while polyarginine‐derived nitric oxide accelerates Fe3+ reduction, leading to self‐amplifying •OH generation for ...
Jun Ma, Jingjing Qiu, Shiren Wang
wiley +1 more source
Subsequent primary cancers in relation to treatment of ovarian cancer [PDF]
, 1989 P Prior, DJ Pope
openalex +1 more source
In vivo cell kinetic effects of cis‐platinum on human ovarian cancer xenografts measured by dual parameter flow cytometry [PDF]
, 1987 Bernd‐Uwe Sevin +4 more
openalex +1 more source
Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases
Advanced Materials, EarlyView.This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu +16 more
wiley +1 more source
Preoperative detection of ovarian cancer by color doppler ultrasonography and CA 125
, 1970 Fawzia Hossain +5 more
openalex +2 more sources
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Advanced Materials, EarlyView.Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi +4 more
wiley +1 more source
Treating ovarian cancer: Authors' reply [PDF]
, 1986 R. W. Burslem, P M Wilkinson
openalex +1 more source
Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers
Journal of the American Medical Association (JAMA), 2017 Karoline B. Kuchenbaecker +59 more
semanticscholar +1 more source