Results 251 to 260 of about 5,337,944 (374)

Biosecurity Primitive: Polymerase X‐based Genetic Physical Unclonable Functions

Advanced Science, EarlyView.
What if every cell line can carry an unforgeable genomic fingerprint—one that proves its origin, ensures its authenticity, and thwarts unauthorized duplication? Here, CRISPR‐induced DNA lesions paired with TdT‐mediated repair produce robust, unique, and unclonable genetic signatures—advancing the concept of molecular Physical Unclonable Functions (PUF)
Zikun Zhou, Taek Kang, Jie Chen, Yesh Doctor, Jocelyn G Camposagrado, Yiorgos Makris, Alexander Pertsemlidis, Leonidas Bleris   +7 more
wiley   +1 more source

Scottish ovarian cancer forum. [PDF]

BMJ Open Qual
Cairns M, Ghaoui Dit Ebef N, Scottish Ovarian Cancer Collaboration.   +2 more
europepmc   +1 more source

Mechanisms and modulation of resistance to chemotherapy in ovarian cancer [PDF]

, 1993
Raymond P. Perez, Thomas C. Hamilton, Robert F. Ozols, Robert C. Young   +3 more
openalex   +1 more source

POLE Deficiency Exacerbates Diesel Engine Exhaust‐Induced Genomic Instability and Malignant Transformation of Bronchial Epithelial Cells

Advanced Science, EarlyView.
This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing（WGS） and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang, Zhaoxu Wu, Qiang Ju, Nuo Xu, Xian Chen, Hongguang Chen, Shuaishuai Yang, Jing Ji, Yanjie Zhao   +8 more
wiley   +1 more source

Modulating ovarian cancer progression through FDX1-driven autophagy. [PDF]

NPJ Precis Oncol
Liu C, Wang S, Zhao J, Qiu H, Du H.
europepmc   +1 more source

Semaphorin 3E‐Plexin‐D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice

Advanced Science, EarlyView.
The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang, Jimmy Dhillon, Paul D. Soloway, Bo Shui, Seoyeon Lee, Jennifer K. Grenier, Paul R. Munn, M. Cecilia Ljungberg, Rebecca B Williams, Rainer B. Lanz, Yu‐Hsiang Liao, Yi A. Ren   +11 more
wiley   +1 more source

Expression and clinical value of EIF3CL in serous ovarian cancer. [PDF]

J Int Med Res
Li T, Liu L, Qiao Q, Lin Z, Yuan J, Zeng Z, Yao J.   +6 more
europepmc   +1 more source

New cytostatic drugs in ovarian cancer

, 1993
Heine H. Hansen, Elizabeth A. Eisenhauer, M Hansen, J.P. Neijt, Martine Piccart, Cristiana Sessa, J.T. Thigpen   +6 more
openalex   +1 more source

Invasive Epithelial Ovarian Cancer Survival by Histotype and Disease Stage

Journal of the National Cancer Institute, 2019
L. Peres, K. Cushing-Haugen, M. Köbel, H. Harris, A. Berchuck, M. Rossing, J. Schildkraut, J. Doherty   +7 more
semanticscholar   +1 more source

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source