Results 261 to 270 of about 5,260,709 (398)

High‐Throughput Proteoform Imaging for Revealing Spatial‐Resolved Changes in Brain Tissues Associated with Alzheimer's Disease

Advanced Science, Volume 12, Issue 17, May 8, 2025.
High‐throughput proteoform imaging (HTPi) is established by combining matrix‐assisted laser desorption ionization mass spectrometry imaging and high‐sensitivity region‐specific top‐down proteomic analysis. HTPi enables the generation of annotated proteoform images with exceptional precision, high throughput, and deep coverage, showing distinct spatial ...
Yue Sun, Dan Liu, Yu Liang, Xue Yang, Xinxin Liu, Baofeng Zhao, Zhen Liang, Yukui Zhang, Lihua Zhang   +8 more
wiley   +1 more source

HIPEC in recurrent ovarian cancer: flogging a tired HORSE? [PDF]

J Gynecol Oncol
Bhatt A, Kazi M, Bhandoria G, Seshadri RA.   +3 more
europepmc   +1 more source

Ovarian cancer [PDF]

Orvosi Hetilap, 2011
Zoltán, Langmár, Sándor, Csömör, Miklós, Németh, Zoltán, Tomcsik, József Gábor, Joó   +4 more
openaire   +2 more sources

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

Advanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao, Chao Yan, Haibo Huang, Shilong Wang, Jiaying Li, Yun Chen, Xiaolu Qu, Qi Bao, Lingna Xu, Yuanyuan Zhang, Danyang Fan, Xia He, Yanwen Liu, Yongsheng Zhang, Yalan Yang, Zhonglin Tang   +15 more
wiley   +1 more source

Promoting equitable genetic testing in ovarian cancer: the demonstration of improvement for molecular ovarian cancer testing (DEMO) project. [PDF]

BMJ Open Qual
Leung EY, Funingana IG, Bird L, Alcaraz ML, Evans A, Considine A, Freeman S, Jimenez-Linan M, Spencer C, Phanasan K, Winning J, Ang JE, Parkinson C, Ong KR, Butler S, Ridgway O, Charles I, Pannell R, Abedin P, Boyle W, Emery J, Salter-Scott J, Williams S, Ganesan R, Sundar S, Balega J, Brenton JD.   +26 more
europepmc   +1 more source

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

Advanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang, Yunjun Li, Di Han, Kun Deng, Wei Gao, Minghua Wu   +5 more
wiley   +1 more source

Diet and survival after a diagnosis of ovarian cancer: a pooled analysis from the Ovarian Cancer Association Consortium. [PDF]

Am J Clin Nutr
Nagle CM, Ibiebele TI, Na R, Bandera EV, Cramer D, Doherty JA, Giles GG, Goodman MT, Hanley GE, Harris HR, Jensen A, Kjaer SK, Lee A, McGuire V, Milne RL, Qin B, Richardson J, Sasamoto N, Schildkraut JM, Sieh W, Terry KL, Titus L, Trabert B, Wentzensen N, Wu AH, Berchuck A, Pike MC, Pearce CL, Webb PM, Multidisciplinary Ovarian Cancer Outcomes Group and Ovarian Cancer Association Consortium.   +29 more
europepmc   +1 more source

The clinical management of ovarian cancer

, 1987
Nina Einhorn
openalex   +1 more source

Targeting Antigen‐Presenting Cells to Enhance the Tumor‐Spleen Immunity Cycle through Liposome‐Neoantigen Vaccine

Advanced Science, EarlyView.
LNPsD18, a cationic liposome that enhances antigen‐presenting cell uptake in the spleen and tumor without targeting ligands is developed. Co‐delivering neoantigens and a TLR9 agonist significantly improve DC activation, tumor immunity, and survival in liver and colorectal cancer models, demonstrating the importance of dual‐site APC targeting for cancer
Yu Xu, Bing Wang, Yue Huang, JianPing Liao, Chenyi Wu, Chenxi Zhou, Zishi Kang, Shiyang Jiang, Bing‐Chen Wu, Da Zhang, Ruihua Xu, Xiaolong Liu, Feng Wang   +12 more
wiley   +1 more source

Immunotherapy in Recurrent Ovarian Cancer. [PDF]

Biomedicines
Chen K, Wang J, Yang M, Deng S, Sun L.
europepmc   +1 more source