Results 281 to 290 of about 5,337,944 (374)
Advanced Science, EarlyView.This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang +18 more
wiley +1 more source
Targeting ferroptosis: a promising avenue for ovarian cancer treatment. [PDF]
Front ImmunolWu X +9 more
europepmc +1 more source
Development of an optimized conditionally replicative adenoviral agent for ovarian cancer
, 1992 David T Curiel
openalex +2 more sources
Journal of the American Medical Association (JAMA), 2018 Jillian T Henderson +2 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie +8 more
wiley +1 more source
Biglycan promotes proliferation and metastasis of ovarian cancer. [PDF]
Int J Clin Exp PatholFang SY, Zhang XM, Chen XP.
europepmc +1 more source
Advanced Science, EarlyView.It is reported that Fn14 inhibited EOC metastasis by regulating Slug‐mediated EMT. Furthermore, Fn14 altered the subcellular localization of SIRT2 by interacting with SIRT2, leading to reduced SIRT2 shuttling into the nucleus and subsequently promoting the acetylated degradation of Slug.
Anyue Wu +9 more
wiley +1 more source
Overexpression of MAFG-AS1 in ovarian cancer promotes glucose metabolism reprogramming and malignant biological behavior of ovarian cancer cells by regulating HIF-1α. [PDF]
Discov OncolJia L, Yu F.
europepmc +1 more source