Results 311 to 320 of about 5,436,787 (348)
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Clinical and translational advances in ovarian cancer therapy
Nature Cancer, 2023P. Konstantinopoulos, U. Matulonis
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Clinical Obstetrics & Gynecology, 2012
Annual screening of asymptomatic postmenopausal women using a combination of transvaginal sonography and serum Ca-125 has been evaluated in 4 major clinical trials as a means to facilitate earlier detection of ovarian cancer. In several trials, screening has caused a decrease in stage at detection.
John R, van Nagell, Edward John, Pavlik
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Annual screening of asymptomatic postmenopausal women using a combination of transvaginal sonography and serum Ca-125 has been evaluated in 4 major clinical trials as a means to facilitate earlier detection of ovarian cancer. In several trials, screening has caused a decrease in stage at detection.
John R, van Nagell, Edward John, Pavlik
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Current Treatment Options in Oncology, 2000
State-of-the-art treatment for advanced ovarian cancer requires a multimodality approach. Aggressive surgical debulking with the goal of optimal cytoreduction is the initial step. After primary cytoreductive surgery, standard treatment for patients with stage III and IV disease is systemic combination chemotherapy consisting of six cycles of paclitaxel
D S, Chi, P, Sabbatini
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State-of-the-art treatment for advanced ovarian cancer requires a multimodality approach. Aggressive surgical debulking with the goal of optimal cytoreduction is the initial step. After primary cytoreductive surgery, standard treatment for patients with stage III and IV disease is systemic combination chemotherapy consisting of six cycles of paclitaxel
D S, Chi, P, Sabbatini
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Critical Reviews in Oncology/Hematology, 2009
At least 10% of ovarian tumors are hereditary and associated with highly penetrant, autosomal, dominant genetic predisposition. Three clinical manifestations of hereditary ovarian cancer have been identified: site-specific ovarian cancer, hereditary breast and/or ovarian cancer (HBOC) and hereditary non-polyposis colorectal cancer (HNPCC) syndromes ...
RUSSO, Antonio +5 more
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At least 10% of ovarian tumors are hereditary and associated with highly penetrant, autosomal, dominant genetic predisposition. Three clinical manifestations of hereditary ovarian cancer have been identified: site-specific ovarian cancer, hereditary breast and/or ovarian cancer (HBOC) and hereditary non-polyposis colorectal cancer (HNPCC) syndromes ...
RUSSO, Antonio +5 more
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The Lancet, 1969
Abstract A family is described in which 5 sisters and their mother had ovarian cancer. Prophylactic oophorectomy was done in five females in the next generation. None of the ovaries showed histological evidence of ovarian carcinoma.
A C, Lewis, B C, Davison
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Abstract A family is described in which 5 sisters and their mother had ovarian cancer. Prophylactic oophorectomy was done in five females in the next generation. None of the ovaries showed histological evidence of ovarian carcinoma.
A C, Lewis, B C, Davison
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Cold Spring Harbor Perspectives in Medicine
Significant advances in basic and translational research have improved our understanding of the molecular alterations and biological vulnerabilities of the different histologic subsets of epithelial ovarian cancer (EOC). This has led to clinical trials that have incorporated novel agents based on molecular aspects into the treatment paradigm for both ...
Diana, Miao +2 more
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Significant advances in basic and translational research have improved our understanding of the molecular alterations and biological vulnerabilities of the different histologic subsets of epithelial ovarian cancer (EOC). This has led to clinical trials that have incorporated novel agents based on molecular aspects into the treatment paradigm for both ...
Diana, Miao +2 more
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Nursing
Abstract: Ovarian cancer, a leading cause of cancer deaths, poses challenges due to insidious development and vague signs and symptoms. Risk factors include age, reproductive history, genetic mutations, and environmental factors. Treatment involves surgery, chemotherapy, and targeted therapy, with nursing interventions focusing on symptom ...
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Abstract: Ovarian cancer, a leading cause of cancer deaths, poses challenges due to insidious development and vague signs and symptoms. Risk factors include age, reproductive history, genetic mutations, and environmental factors. Treatment involves surgery, chemotherapy, and targeted therapy, with nursing interventions focusing on symptom ...
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Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer.
Science, 1989D. Slamon +10 more
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