Results 41 to 50 of about 197,955 (298)

Malignant transformation of endometriosis: pearls and pitfalls at magnetic resonance imaging

Опухоли женской репродуктивной системы, 2014
The article analyzes magnetic resonance images of the 117 patients with endometrioid ovarian cysts including 12 patients with ovarian cancer raised from endometrioid cysts.
Ye. A. Yukhno, I. A. Trofimenko, G. Ye. Trufanov   +2 more
doaj   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Ovarian cyst removal influences ovarian reserve dependent on histology, size and type of operation

Women's Health, 2018
Previous publications suggest a reduction in the ovarian reserve following ovarian surgery. The influence of the underlying disease, histology, size of the ovarian cyst and type of procedure remains unclear.
Melanie Henes, Tobias Engler, Florin-Andrei Taran, Sara Brucker, Katharina Rall, Birthe Janz, Barbara Lawrenz   +6 more
doaj   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

Huge bilateral ovarian cysts in adulthood as the presenting feature of Van Wyk Grumbach syndrome due to chronic uncontrolled juvenile hypothyroidism

Indian Journal of Endocrinology and Metabolism, 2013
Juvenile primary hypothyroidism causing cystic ovaries and pseudoprecocious puberty (Van-Wyk Grumbach syndrome (VWGS)) is well documented in literature. There are only a few reports of primary hypothyroidism presenting as ovarian cysts in adults. Here we
K S Shivaprasad, Deep Dutta, Rajesh Jain, Manoj Kumar, Indira Maisnam, Dibakar Biswas, Sujoy Ghosh, Satinath Mukhopadhyay, Subhankar Chowdhury   +8 more
doaj   +1 more source

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

Advanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han, Qin Yuan, Zhu Wu, Yaohui Fang, Hong Qian, Jiale Zhu, Yuchen Zhang, Ke Deng, Liangliang Su, Haibo Xu, Haotian Shu, Yiming Gong, Qiaoqiao Xu, Guizhen Du, Di Wu, Yun Fan, Chuncheng Lu   +16 more
wiley   +1 more source

The influence of ovarian cyst type and size on ovarian reserve markers: implications for fertility counseling and preservation strategy

Frontiers in Endocrinology
BackgroundOvarian cysts are common in reproductive-aged women and may affect ovarian reserve, thereby impacting fertility potential. This study aimed to evaluate the differential impact of various ovarian cyst types and sizes on ovarian reserve markers ...
Xingyu Sun, Doudou Liu, Zijing Guo, Lijuan He, Shaohua Wang   +4 more
doaj   +1 more source

Ovarian cysts and cyclic hormone replacement therapy: is there an association?

Acta Obstetricia et Gynecologica Scandinavica, 1997
Objectives. To evaluate whether there may be an association between postmenopausal ovarian cysts and hormone replacement therapy. Methods. The study comprised 564 consecutive, asymptomatic, postmenopausal women who were referred for routine, transvaginal
Itai Bar‐Hava, Raoul Orvieto, David Vardimon, Yoram Manor, Ariel Weissman, Roni Nelinger, Zion Ben‐Rafael   +6 more
doaj   +1 more source

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source