Results 61 to 70 of about 1,085,590 (343)

An unusual ovarian cyst

open access: yesJournal of Obstetrics and Gynaecology, 2014
A 68-year-old woman presented to the cardiologist with a twelve-month history of leg swelling, shortness of breath and fatigue.
N, Rambocas, D, Murphy
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Loss of PKBβ/Akt2 predisposes mice to ovarian cyst formation and increases the severity of polycystic ovary formation in vivo

open access: yesDisease Models & Mechanisms, 2012
SUMMARY Ovarian cysts affect women of all ages and decrease fertility. In particular, polycystic ovarian syndrome (PCOS), in which multiple follicular cysts develop, affects 5–10% of women of reproductive age and can result in infertility.
David F. Restuccia   +2 more
doaj   +1 more source

Human epididymis protein 4 (HE4) in benign and malignant diseases [PDF]

open access: yes, 2012
Background: Human epididymis protein 4 (HE4) is described as a useful new biomarker in ovarian cancer. As HE4 is neither tumor nor organ specific, we intensively investigated the occurrence of this protein in female and male patients with various benign ...
Anastasi   +39 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Case Series on Pregnant Patients with Ovarian Cysts and Management of Potential Complications

open access: yesIndonesian Journal of Obstetrics and Gynecology
(English) Objective: To report a series of ovarian cyst cases in pregnancy that we diagnosed in our obstetrics and gynecology department; and to provide literary perspective in management of potential complications.
Gezta Nasafir Hermawan   +1 more
doaj   +1 more source

HE4 in the differential diagnosis of ovarian masses [PDF]

open access: yes, 2015
Ovarian masses, a common finding among pre- and post-menopausal women, can be benign or malignant. Ovarian cancer is the leading cause of death from gynecologic malignancy among women living in industrialized countries.
ANASTASI, Emanuela   +5 more
core   +1 more source

Tuberculous Ovarian Cysts [PDF]

open access: yesThe American Journal of the Medical Sciences, 1906
n ...
openaire   +1 more source

Successful Conservative Management of Ruptured Ovarian Cysts with Hemoperitoneum in Healthy Women

open access: yesPLoS ONE, 2014
Study Objective To determine the success rate of the “intended conservative management strategy” of ruptured ovarian cysts with hemoperitoneum and the risk factors for surgical interventions in healthy women of reproductive age.
J. Kim   +10 more
semanticscholar   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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