Results 11 to 20 of about 2,653,643 (293)
Ovarian cancer and BRCA mutation genetic testing: the Brazilian reality
Introduction: Ovarian cancer (OC) is one of the leading causes of women’s cancer deaths worldwide. Recent clinical trials with PARP inhibitors showed promising therapeutic opportunities for OC patients. The assessment of BRCA mutation is well established
Dalila Cunha de Oliveira +6 more
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Tumor marker CA-125 in adnexal inflammatory tumors [PDF]
Background/Aim. The glycoprotein of a high molecular weight CA-125, which is not a specific tumor marker of ovarian cancer, is secreted by the endothelial cells of most pelvic organs. Endometriosis, inflammatory processes in the pelvic cavity, as well as
Nikolić Branka +2 more
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Performance of Ovarian Response Prediction Index As Predictor of Ovarian Response
Objective: We aimed to evaluate potential predictors of response to controlled ovarian stimulation (COS), including follicle stimulating hormone (FSH), Estradiol, antral follicle count (AFC), and ovarian response prediction index (ORPI). Methods: In this
Bolormaa Dagvadorj +5 more
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Ovarian Biomechanics: From Health to Disease
Biomechanics is a physical phenomenon which mainly related with deformation and movement of life forms. As a mechanical signal, it participates in the growth and development of many tissues and organs, including ovary.
Chenchen Sun +4 more
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Investigating the potential for expediting diagnosis of ovarian cancer via prompt symptom recognition & "targeted screening" [PDF]
PhDThis thesis explores the potential for using symptoms as a tool to bring forward the diagnosis of ovarian cancer. Current evidence supports the existence of prediagnostic symptoms, however symptom lead time has yet to be adequately quantified ...
Lim, Anita Wey Wey
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RUNX1-Regulated Signaling Pathways in Ovarian Cancer
Ovarian cancer is the leading cause of gynecological death worldwide, and its poor prognosis and high mortality seriously affect the life of ovarian cancer patients.
Yuanzhi Chen, Yingying He, Shubai Liu
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Objective: Apolipoprotein A1 (ApoA1) is remarkably decreased in serum and ovarian tissues of ovarian cancer patients. ApoA1 and ApoA1 mimetic peptides can sequestrate pro-inflammatory phospholipids, some of which are known to activate a variety of ...
Aline T. Marinho +8 more
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Human epididymis protein 4 (HE4) in benign and malignant diseases [PDF]
Background: Human epididymis protein 4 (HE4) is described as a useful new biomarker in ovarian cancer. As HE4 is neither tumor nor organ specific, we intensively investigated the occurrence of this protein in female and male patients with various benign ...
Kirschenhofer, Angela +9 more
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Polyamines in Ovarian Aging and Disease
Ovarian aging and disease-related decline in fertility are challenging medical and economic issues with an increasing prevalence. Polyamines are a class of polycationic alkylamines widely distributed in mammals. They are small molecules essential for cell growth and development.
Bo Kang +7 more
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PREMATURE OVARIAN INSUFFICIENCY IN SYSTEMIC SCLEROSIS
The early onset of ovarian aging results in decreased ovarian reserve and premature ovarian insufficiency (POI), leading to infertility and early menopause. POI is associated with systemic autoimmune diseases.
Neslihan Gokcen
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