Results 121 to 130 of about 55,590 (315)

Establishing a Quantitative Framework for Combined Oral Contraceptives: Evaluating the Impact of Drug–Drug Interactions on Exposure and Clinical (Surrogate) Efficacy Endpoints

The Journal of Clinical Pharmacology, EarlyView.
Abstract According to the FDA Guidance for Industry on Clinical Drug Interaction (DDI) Studies with Combined Oral Contraceptives (COCs), sponsors are expected to conduct dedicated clinical DDI studies if in vitro findings suggest weak or moderate CYP3A induction, while concomitant use of COCs with strong inducers should be avoided. The guidance further
Dain Chun, Huili Chen, Brian Cicali, Serge Guzy, Joachim Hoechel, Tianze Jiao, Valvanera Vozmediano, Stephan Schmidt   +7 more
wiley   +1 more source

Determination of the effects of bone marrow derived mesenchymal stem cells and ovarian stromal stem cells on follicular maturation in cyclophosphamide induced ovarian failure in rats

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: Chemotherapy causes depletion of primordial follicles that leads to premature ovarian failure in female cancer survivals. We investigated the effect of bone marrow derived mesenchymal (BMMSCs) and ovarian stromal stem cells (OSSCs) on follicle
Huseyin Erdinc Besikcioglu, Gulistan Sanem Sarıbas, Candan Ozogul, Meral Tiryaki, Sevtap Kilic, Ferda Alpaslan Pınarlı, Ozlem Gulbahar   +6 more
doaj  

Steroid Hormone Formation in Bovine Ovarian Follicles

, 1975
Takahide Mori
openalex   +2 more sources

Modulation of Functional Capacity of Small Ovarian Follicles in the Post-partum Cow by Prolactin [PDF]

, 1981
TJ Weiss, CD Nancarrow, Armstrong Dt, JB Donnelly   +3 more
openalex   +1 more source

Telomere‐Related Gene Networks in the Ovary Shift Across Environmental Factors

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ovary is key to linking environmental factors with the timing and quality of offspring development. Focused on free‐living female tree swallows (Tachycineta bicolor), we measured temporal variation in ovarian expression of genes involved in the regulation of telomere length.
Sarah E. Wolf, Elizabeth M. George, Jess Dong, Kimberly A. Rosvall   +3 more
wiley   +1 more source

The binding of rat luteinizing hormone (.GAMMA.LH), rat follicle stimulating hormone (.GAMMA.FSH) and rat prolactin (.GAMMA.PRL) to dissociated cells of luteinized ovaries and intrasplenic ovarian grafts.

, 1978
Takako SAIGA-NARUMI, Seiichiro Kawashima
openalex   +2 more sources

Induction of Male Courtship Behavior by Olfactory Cues Released From Ovulating Female in the Medaka, Oryzias latipes

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Chemical communication between males and females is important for successful reproduction of animals. The activation of male courtship behavior by female olfactory cues has only been demonstrated in a limited number of teleost species. In the present study, we showed that in the model animal medaka, courtship behavior in males are activated by
Yasunori Koya, Megumi Kodama, Tsukasa Maruyama, Yuki Kondo   +3 more
wiley   +1 more source

Correction: Spatial regulation of Drosophila ovarian Follicle Stem Cell division rates and cell cycle transitions. [PDF]

PLoS Genet, 2023
Melamed D, Choi A, Reilein A, Tavaré S, Kalderon D.   +4 more
europepmc   +1 more source

The Relationship of Estrogen Changes With Sinonasal Symptoms and Disease in Women: A Scoping Review

The Laryngoscope, EarlyView.
The purpose of this scoping review was to assess the existing epidemiologic literature looking at the relationship of estrogen on sinonasal symptoms in women. PubMed and Embase were searched and 57 articles were chosen for analysis. Overall, the literature is heterogeneous but limited and so estrogen as mediator in sinonasal disease is an important ...
Snehitha Talugula, Margaret A. Chervinko, Andrea Cespedes Zablah, Isabella Cano, Dara R. Adams, Anthony I. Dick, Victoria S. Lee   +6 more
wiley   +1 more source

The value of low-intensity pulsed ultrasound in reducing ovarian injury caused by chemotherapy in mice

Reproductive Biology and Endocrinology
Background Ovarian damage and follicle loss are major side effects of chemotherapy in young female patients with cancer. However, effective strategies to prevent these injuries are still lacking.
Yi Zhou, Fengyu Zhu, Yuanyuan Zhou, Xuqing Li, Shuhan Zhao, Yiqing Zhang, Ying Zhu, Hongyan Li, Yunxia Cao, Chaoxue Zhang   +9 more
doaj   +1 more source