A double‐positive surface marker detection approach was developed to conduct exosome surface protein detection in serum samples. It reaches single‐exosome detection, and over 300 exosome protein parameters are analyzed. The diagnostic accuracy achieved 90% in differentiation of high‐grade serous/serous ovarian carcinoma patients, benign patients, and ...
Jiaoyan Qiu+7 more
wiley +1 more source
Evaluation of ovarian functions in girls treated for hematological malignancy
Acute lymphoblastic leukemia (ALL) and other hematological malignancies are the most common cancers in children, with chemotherapy and/or radiotherapy as the primary treatment options.
Şule Çalışkan Kamış+3 more
doaj +1 more source
Stromal Senp1 promotes mouse early folliculogenesis by regulating BMP4 expression
Background Mammalian folliculogenesis, maturation of the ovarian follicles, require both growth factors derived from oocyte and surrounding cells, including stromal cells.
Shu Tan+7 more
doaj +1 more source
Efficient Precision Control in Object Detection Models for Enhanced and Reliable Ovarian Follicle Counting [PDF]
Image analysis is a key tool for describing the detailed mechanisms of folliculogenesis, such as evaluating the quantity of mouse Primordial ovarian Follicles (PMF) in the ovarian reserve. The development of high-resolution virtual slide scanners offers the possibility of quantifying, robustifying and accelerating the histopathological procedure.
arxiv +1 more source
Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai+6 more
wiley +1 more source
Effect of supplementation with different fat sources on the mechanisms involved in reproductive performance in lactating dairy cattle [PDF]
peer reviewedSupplementary fat positively influences reproductive performance in dairy cattle, although the mechanisms involved are not clearly defined. Our objective was to determine the effects of four different fat supplements on follicle development,
Butler, Stephen+6 more
core +1 more source
Mechanisms of fibroblast growth factor signaling in the ovarian follicle.
Fibroblast growth factors (FGFs) have been shown to alter growth and differentiation of reproductive tissues in a variety of species. Within the female reproductive tract, the effects of FGFs have been focused on the ovary, and the most studied one is ...
C. Price
semanticscholar +1 more source
Pre‐oviposition development of the brown anole (Anolis sagrei)
Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling+9 more
wiley +1 more source
Ovarian follicle selection and granulosa cell differentiation.
The reproductive strategy for avian species that produce a sequence (or clutch) of eggs is dependent upon the maintenance of a small cohort of viable, undifferentiated (prehierarchal) follicles.
Alan Leslie Johnson
semanticscholar +1 more source
Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis [PDF]
Despite the well-established tumor suppressive role of TGFβ proteins, depletion of key TGFβ signaling components in the mouse ovary does not induce a growth advantage.
Bartholin, Laurent+5 more
core +1 more source