Results 201 to 210 of about 307,578 (312)
Interplay of Oxidative Stress, Autophagy, and Rubicon in Ovarian Follicle Dynamics: Orchestrating Ovarian Aging. [PDF]
Yamada K +11 more
europepmc +1 more source
This study characterizes heterogeneous mottled grayscale ultrasound echoes of ovarian immature teratoma as the “pebbled mosaic sign,” noting solid lesions correlate with advanced pathological grades. Preoperative identification of immature tissue informs operative stratification. Abstract Introduction Ovarian immature teratomas (ITs) are rare malignant
Tianyu Zhang +7 more
wiley +1 more source
Advances in ovarian follicle culture systems: exploring the interplay between cells, matrix, and ovarian architecture. [PDF]
Luciano AM +6 more
europepmc +1 more source
Introduction There are notable differences between the platypus and common species of domestic mammal in the location and structure of some abdominal organs. The aim of this study was to detail the size, position and relative locations of organs in the left side of the platypus abdomen, to assist evidence‐based decision‐making in a clinical setting ...
JW Macgregor +6 more
wiley +1 more source
Effects of DSS-induced intestinal disruption on egg quality and brain, liver, and ovarian follicle functions in laying hens. [PDF]
Aprianto MA, Jaisue J, Isobe N, Nii T.
europepmc +1 more source
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert +2 more
wiley +1 more source
BEZ235-Mediated PI3K/mTOR dual inhibition improves ovarian follicle survival in a preclinical model. [PDF]
Bindels J +4 more
europepmc +1 more source
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Automatic ovarian follicle detection using object detection models. [PDF]
Hassan MH, Reiter E, Razzaq M.
europepmc +1 more source
Targeting KRAS for cancer therapy
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia +4 more
wiley +1 more source

