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Genetic Association and Drug Target Exploration Between Inflammation-Related Proteins and the Risk of Primary Ovarian Insufficiency. [PDF]
J Inflamm ResWang C, Lin XH, Yang XJ.
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Premature ovarian insufficiency
BMJPremature ovarian insufficiency (POI) is a cause of infertility and endocrine dysfunction in women, defined by loss of normal, predictable ovarian activity before the age of 40 years. POI is clinically characterized by amenorrhoea (primary or secondary) with raised circulating levels of follicle-stimulating hormone.
Philippe Touraine +5 more
semanticscholar +12 more sources
Premature ovarian insufficiency
Current Opinion in Endocrine and Metabolic Research, 2023Natural menopause typically occurs between the ages of 46 to 55 years. Premature ovarian insufficiency or premature menopause refers to compromised ovarian follicular activity, occurring spontaneously or because of medical interventions, prior to the age of 40 years.
Svetlana Vujovic +4 more
openaire +3 more sources
The Lancet, 2010
Primary ovarian insufficiency is a subclass of ovarian dysfunction in which the cause is within the ovary. In most cases, an unknown mechanism leads to premature exhaustion of the resting pool of primordial follicles. Primary ovarian insufficiency might also result from genetic defects, chemotherapy, radiotherapy, or surgery.
De Vos, Michel +2 more
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Primary ovarian insufficiency is a subclass of ovarian dysfunction in which the cause is within the ovary. In most cases, an unknown mechanism leads to premature exhaustion of the resting pool of primordial follicles. Primary ovarian insufficiency might also result from genetic defects, chemotherapy, radiotherapy, or surgery.
De Vos, Michel +2 more
+7 more sources
The global prevalence of premature ovarian insufficiency: a systematic review and meta-analysis
Climacteric, 2022Objective The objective of this review was to answer the global prevalence of premature ovarian insufficiency (POI), and explore the associated factors including etiopathology and regions with POI. Methods The search was conducted on reports from a total
M. Li +5 more
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Primary Ovarian Insufficiency and Ovarian Aging
Obstetrics and Gynecology Clinics of North America, 2023Primary ovarian insufficiency (POI) is a complex condition of aberrant ovarian aging. POI etiologies are varied, and most cases have no identifiable underlying cause. Caring for women with POI requires an approach that understands the importance of ovarian function in a variety of target organs and tissues.
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Premature ovarian insufficiency, early menopause, and induced menopause.
Best practice & research. Clinical endocrinology & metabolism, 2023Premature ovarian insufficiency (POI) is a condition in which there is a decline in ovarian function in women who are younger than 40 years resulting in a hypo-oestrogenic state with elevated gonadotrophins and oligomenorrhoea/amenorrhoea.
Haitham Hamoda, Angela Sharma
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Autoimmune primary ovarian insufficiency
Autoimmunity Reviews, 2014Primary ovarian insufficiency (POI) is defined as sustained amenorrhea, increased follicle-stimulating hormone and low estrogen levels, whereas diminished ovarian reserve (DOR) is characterized as regular menses and alterations of ovarian reserve tests.
C A, Silva +5 more
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Seminars in Reproductive Medicine, 2016
Primary ovarian insufficiency (POI), also known as premature ovarian failure or premature menopause, is defined as cessation of menstruation before the expected age of menopause. Potential etiologies for POI can be divided into genetic, autoimmune, and iatrogenic categories.
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Primary ovarian insufficiency (POI), also known as premature ovarian failure or premature menopause, is defined as cessation of menstruation before the expected age of menopause. Potential etiologies for POI can be divided into genetic, autoimmune, and iatrogenic categories.
openaire +4 more sources