Niraparib in ovarian cancer. results to date and clinical potential [PDF]
, 2017 Ovarian cancer is the first cause of death from gynaecological malignancy. Germline mutation in BRCA1 and 2, two genes involved in the mechanisms of reparation of DNA damage, are showed to be related with the incidence of breast and ovarian cancer, both ...
Benedetti Panici, Pierluigi +5 more
core +1 more source
Clinicomorphological Study Of Ovarian Lesions
Journal of Chitwan Medical College, 2014 This prospective study was conducted at College of Medical Sciences-Teaching Hospital (CMS-TH) during December 2008 to May 2010. One hundred and fifty cases were analyzed. Age of the patients, parity, presenting symptoms, types of surgery, clinical diagnosis and complications were retrieved from case sheets.
openaire +2 more sources
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Unleashing low T2 magnetic resonance imaging signal of the ovary: a radiologic diagnostic approach
The Egyptian Journal of Radiology and Nuclear MedicineBackground To illustrate and properly diagnose the different neoplastic and non-neoplastic low T2 signal lesions of the ovary using a radiologic diagnostic approach to reach a proper management plan.
Shereen AbdelRaouf +3 more
doaj +1 more source
Unique Molecular Features in High-Risk Histology Endometrial Cancers [PDF]
, 2019 Endometrial cancer is the most common gynecologic malignancy in the United States and the sixth most common cancer in women worldwide. Fortunately, most women who develop endometrial cancer have low-grade early-stage endometrioid carcinomas, and simple ...
Collins, Kaitlyn +4 more
core +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
The Diagnostic Accuracy of Abdominal Ultrasound Imaging for Detection of Ovarian Masses [PDF]
Background/Objective: Detection of the tissue diagnosis of ovarian space occupying lesions (OSOL) has remained a challenging task for sonographers since many adnexal masses have nonspecific sonographic appearances.
رفاهی, سهیلا +2 more
core
A Rare Xanthogranulomatous Oophoritis Presenting as Ovarian Cancer [PDF]
, 2012 Xanthogranulomatous inflammation is an uncommon form of chronic inflammation that is destructive to affected organs; it is characterized by the presence of lipid-filled macrophages with admixed lymphocytes, plasma cells, and neutrophils. Only a few cases
Bafna, UD +5 more
core
Comment on "Research on values of GDF-15 level in the diagnosis of primary liver cancer and evaluation of chemotherapeutic effect" [PDF]
, 2019 Comment on research on values of GDF-15 level in the diagnosis of primary liver cancer and evaluation of chemotherapeutic ...
Berretta, S, Fisichella, R, Izzo, L
core +1 more source
T2-weighted imaging hypointensity in an ovarian lesion: is it a benign finding? [PDF]
Einstein (Sao Paulo), 2022 Alcala JMF +3 more
europepmc +1 more source