Results 31 to 40 of about 97,449 (305)

Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair and p53. [PDF]

, 2013
The antitumor prodrug Temozolomide is compromised by its dependence for activity on DNA mismatch repair (MMR) and the repair of the chemosensitive DNA lesion, O6-methylguanine (O6-MeG), by O6-methylguanine-DNA-methyltransferase (EC 2.1.1.63, MGMT). Tumor
Arris C. E., Arrowsmith J., Barvaux V. A., Boberg F., Boyd M. R., Bunz F., Damera K., Darkes M. J. M., De K., Denny B. J., Dimitrios Pletsas, Dinca E. B., Elrashied A. E. Garelnabi, Garelnabi E. A. E., Hirose Y., Honnalli S. S., Judson P. L., Karran P., Karran P., Kotera M., Leteurtre F., Li Li, Liu L., McElhinney R. S., McGarrity J. F., Mladek A. C., Nishizuka S., Pletsas D., Richard T. Wheelhouse, Roger M. Phillips, Sarkaria J. N., Schmidt B. F., Schmiedekamp A., Shealy Y. F., Siddiqui A. A., Smith R. H., Stevens M. F. G., Svilar D., Wang Y., Wheelhouse R. T., Wheelhouse R. T., Zhang J., Zhang J.   +42 more
core   +1 more source

Adnexal Masses: Benign Ovarian Lesions and Characterization [PDF]

, 2017
Incidental adnexal masses are commonly identified in radiologists’ daily practice. Most of them are benign ovarian lesions of no concern. However, sometimes defining the origin of a pelvic mass may be challenging, especially on ultrasound alone. Moreover, ultrasound not always allows the distinction between a benign and a malignant adnexal tumor.
Schlattau, Alexander, Cunha, Teresa Margarida, Forstner, Rosemarie   +2 more
openaire   +2 more sources

Surgically treated ovarian lesions in preadolescent girls [PDF]

Acta Obstetricia et Gynecologica Scandinavica, 2019
AbstractIntroductionThe purpose of this study was to investigate the epidemiology and characteristics of surgically treated ovarian lesions in preadolescent girls.Material and methodsThis was a retrospective cohort study including all 0‐ to 11‐year‐old girls operated at a single center from 1999 to 2016 for ovarian cysts, neoplasms or torsions. Patient
Liisi Ripatti, Mervi Taskinen, Antti Koivusalo, Seppo Taskinen   +3 more
openaire   +4 more sources

An Uncommon Case of Adolescent Ovarian Teratoma Incarcerated in Inguinal Hernia

Case Reports in Pediatrics, 2016
Mature cystic teratoma is the most frequent benign ovarian neoplastic lesion in adolescents and is generally composed of fully differentiated tissue arising from multipotential three germinal layers.
Marco Pensabene, Vincenza Girgenti, Marcello Cimador, Giuseppe Li Voti, Vito Rodolico, Fortunato Siracusa   +5 more
doaj   +1 more source

To Study Clinicopathological Spectrum of Ovarian Tumour and Tumour Like Lesions in a Tertiary Health Care Centre of North India

JK Science, 2023
Introduction: Variety of primary ovarian neoplasms reflects the complex function of the ovary. The study was conducted to know distribution of ovarian lesions, analyse their mode of presentation and distribution of various morphological pattern of ...
Surbhi Mahajan, Deepti Gupta, Aishvarya Jandial, Subhash Bhardwaj   +3 more
doaj  

Ovarian Masses: Hitting the Oncological Dart with Ultrasound and CT - A Comparative Study in a Remote Northeast Indian Town [PDF]

International Journal of Anatomy Radiology and Surgery, 2017
Introduction: Ovarian cancer is the second most common gynecological malignancy in Indian women after cervical carcinoma. It is a giant killer with the worst prognosis amongst all gynecological malignancies, primarily due to late diagnosis. Therefore,
Manali Arora, Vishal Dhirenbhai Thakker, Geetika Sindhwani, Rudra Kant Gogoi   +3 more
doaj   +1 more source

Co‐existing monophasic teratoma and uterine adenocarcinoma in a female dog [PDF]

, 2019
Ovarian teratomas are occasionally reported in dogs; the rarest type is the monophasic teratoma,composed of tissues originating from only one germ layer. Canine endometrial adenocarcinomas are also rare in dogs and mainly affect geriatric females.
Catarino, J.C, Faim, S., Freire, A., Neves, T., Orge, L., Payan-Carreira, R., Pires, M.A., Seixas, F., Vilhena, H.   +8 more
core   +2 more sources

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Functional MRI in the pre-operative assessment of GI-RADS 3, 4, and 5 ovarian masses

The Egyptian Journal of Radiology and Nuclear Medicine, 2019
Background Characterization of an ovarian lesion is a diagnostic challenge. A correct preoperative assessment is of great importance so as to arrange adequate therapeutic procedures.
Rania S. M. Ibrahim, Manar A. E. L. O. Maher, Solava Abdalaziz, Samar Amer, Doaa Shafie, Soha T. Hamed   +5 more
doaj   +1 more source

Pseudoprecocious puberty due to functional cystic juvenile granulosa cell tumor of the ovary in a 5-year-old girl

Journal of Mahatma Gandhi Institute of Medical Sciences, 2016
A 5-year-old girl child presented with features of pseudoprecocious puberty in the form of bleeding per vaginum and bilateral breast enlargement since 10 days.
Shailaja Prabhala, Jayashankar Erukkambattu, Karthikbabu Perumalla, Annapurna Srirambhatla, Ramamurti Tanikella   +4 more
doaj   +1 more source