Results 41 to 50 of about 97,449 (305)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Massive Ovarian Oedema in a 23-year-old Patient: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Massive Ovarian Oedema (MOE) is a rare gynaecological disorder that has been rarely reported in our country. Approximately six cases have been reported previously in India.
Supriya Mehrotra, Bandana Mehrotra, Sanjay Mehrotra, Ashok Kumar Kapoor, Hari Shyam   +4 more
doaj   +1 more source

Defective DNA repair mechanisms in prostate cancer: impact of olaparib [PDF]

, 2017
The field of prostate oncology has continued to change dramatically. It has truly become a field that is intensely linked to molecular genetic alterations, especially DNA-repair defects.
De Felice, Francesca, Marampon, Francesco, Marchetti, Claudia, Musella, Angela, Tombolini, Vincenzo   +4 more
core   +2 more sources

Methylomic Landscapes of Ovarian Cancer Precursor Lesions

Clinical Cancer Research, 2020
Abstract Purpose: The current paradigm in the development of high-grade serous ovarian carcinoma (HGSC) proposes that the majority of HGSCs arise from precursor serous tubal intraepithelial carcinoma (STIC) lesions of the fallopian tube.
Thomas R, Pisanic, Yeh, Wang, Hanru, Sun, Michael, Considine, Lihong, Li, Tza-Huei, Wang, Tian-Li, Wang, Ie-Ming, Shih   +7 more
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Dye diffusion during laparoscopic tubal patency tests may suggest a lymphatic contribution to dissemination in endometriosis: A prospective, observational study [PDF]

, 2019
Aim Women with adenomyosis are at higher risk of endometriosis recurrence after surgery. This study was to assess if the lymphatic vessel network drained from the uterus to near organs where endometriosis foci lied.
Bonaccorsi, G., Greco, P., Noventa, M., Pesci, A., Scardapane, A., Scioscia, M., Zamboni, G.   +6 more
core   +1 more source

Study of Ovarian Neoplastic Lesions

IOSR Journal of Dental and Medical Sciences, 2016
Ovaries are paired structures with an embryological, anatomic and functional complexity. Changes in their volume can be observed at ovulation, pregnancy and after menopause. Ovaries are normally resistant to diseases, but still ovary can be seat of more number of neoplastic lesions of benign and malignant.
Annapurna Parvatala, Ragidi Ramesh Babu, Natta Bharat Rao, K. Narasimhulu   +3 more
openaire   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Management of ovarian cysts in infants

Journal of Research in Medical Sciences, 2015
Background: To discuss the experience of diagnosis and treatment of ovarian cyst in infants. Materials and Methods: A retrospective review was conducted on 20 infants who suffered from ovarian cyst.
Yan Xue-qiang, Zheng Nan-nan, Yu Lei, Lu Wei, Bian Hong-qiang, Yang Jun, Duan Xu-fei, Qin Xin-ke   +7 more
doaj   +1 more source

Nerve fibres in ovarian endometriotic lesions in women with ovarian endometriosis [PDF]

Human Reproduction, 2009
Although nerve fibres are present in eutopic and ectopic endometrium, it is unclear whether they appear in ovarian endometriotic lesions. We investigated the presence of nerve fibres in ovarian endometriotic lesions and its correlation with clinical parameters in women with ovarian endometriosis.Histological sections of ovarian endometriotic lesions ...
Xinmei, Zhang, Huijiao, Yao, Xiufeng, Huang, Bangchun, Lu, Hong, Xu, Caiyun, Zhou   +5 more
openaire   +2 more sources