Results 61 to 70 of about 97,449 (305)

Practical guidance for applying the ADNEX model from the IOTA group to discriminate between different subtypes of adnexal tumors. [PDF]

, 2015
All gynecologists are faced with ovarian tumors on a regular basis, and the accurate preoperative diagnosis of these masses is important because appropriate management depends on the type of tumor. Recently, the International Ovarian Tumor Analysis (IOTA)
Anthoulakis, C, Bourne, T, Froyman, W, Kaijser, J, Landolfo, C, Timmerman, D, Van Calster, B, Van Hoorde, K, Vergote, I, Wynants, L   +9 more
core   +1 more source

Benign lesions that mimic cancer: Ovarian [PDF]

Cancer Imaging, 2015
As ovarian masses are common in both pre- and in postmenopausal age, a life time risk of up to 5-10% to undergo pelvic surgery has been reported [1]. However, the likelihood of malignancy in these lesions is extremely low. Imaging, particularly, US and MRI, have been integrated as diagnostic tools to better define indications for adequate surgery and ...
Forstner, Rosemarie, Meissnitzer, Thomas, Meissnitzer, Matthias   +2 more
openaire   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Gorlin syndrome presenting with a unilateral ovarian fibroma in a 22-year-old woman: a case report

Journal of Medical Case Reports, 2012
Introduction Nevoid basal cell carcinoma syndrome, or Gorlin syndrome, is an inherited disorder characterized by malignancies of the skin and other organs, skeletal abnormalities, and congenital malformations.
Finch Terence, Pushpanathan Chitra, Brown Krista, El-Gohary Yasser   +3 more
doaj   +1 more source

Ovarian Fibroma with Meigs Syndrome associated with Elevated CA125 - A Rare Case [PDF]

, 2010
Postmenopausal women with solid adnexal masses, ascites and pleural effusion with elevated CA 125 are highly suggestive for malignant ovarian tumor. However in literature 28 cases Meigs syndrome (Benign ovarian tumor, ascites and right pleural effusion ...
Bafna, UD, Balaiah, K, Gnana Prakash, S, Shetty, PK   +3 more
core  

Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications. [PDF]

, 2013
Ewing sarcoma occurs in children, adolescents and young adults. High STAT3 levels have been reported in approximately 50% of patients with Ewing sarcoma, and may be important in tumorigenesis.
Anderson, Peter M, Angelo, Laura S, Benjamin, Robert S, Fu, Siqing, Herzog, Cynthia E, Janku, Filip, Jiang, Yunyun, Kurzrock, Razelle, Naing, Aung, Subbiah, Vivek   +9 more
core   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Acute abdomen with a misleading clinical entity

SAGE Open Medical Case Reports, 2017
Massive ovarian edema is a rare, non-neoplastic solid tumor-like lesion. It results from compromised venous and lymphatic drainage due to partial or intermittent torsion of ovarian pedicle.
Jitendra Singh Nigam, Pushpanjali Ojha, Chitrawati Bal Gargade, Archana Hemant Deshpande   +3 more
doaj   +1 more source

Over-reassurance and undersupport after a 'false alarm': a systematic review of the impact on subsequent cancer symptom attribution and help seeking [PDF]

, 2015
This literature review examined research into the impact of a previous 'all-clear' or non-cancer diagnosis following symptomatic presentation ('false alarm') on symptom attribution and delays in help seeking for subsequent possible cancer ...
Renzi, C, Wardle, J, Whitaker, KL
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source