Results 11 to 20 of about 30,112 (235)

Genome-wide significant risk associations for mucinous ovarian carcinoma [PDF]

Nature Genetics, 2015
Genome-wide association studies have identified several risk associations for ovarian carcinomas but not for mucinous ovarian carcinomas (MOCs). Our analysis of 1,644 MOC cases and 21,693 controls with imputation identified 3 new risk associations: rs752590 at 2q13 (P = 3.3 × 10(-8)), rs711830 at 2q31.1 (P = 7.5 × 10(-12)) and rs688187 at 19q13.2 (P ...
Kelemen, LE, Lawrenson, K, Tyrer, J, Li, Q, Lee, JM, Seo, J-H, Phelan, CM, Beesley, J, Chen, X, Spindler, TJ, Aben, KKH, Anton-Culver, H, Antonenkova, N, Baker, H, Bandera, EV, Bean, Y, Beckmann, MW, Bisogna, M, Bjorge, L, Bogdanova, N, Brinton, LA, Brooks-Wilson, A, Bruinsma, F, Butzow, R, Campbell, IG, Carty, K, Chang-Claude, J, Chen, YA, Chen, Z, Cook, LS, Cramer, DW, Cunningham, JM, Cybulski, C, Dansonka-Mieszkowska, A, Dennis, J, Dicks, E, Doherty, JA, Doerk, T, du Bois, A, Duerst, M, Eccles, D, Easton, DT, Edwards, RP, Eilber, U, Ekici, AB, Engelholm, SA, Fasching, PA, Fridley, BL, Gao, Y-T, Gentry-Maharaj, A, Giles, GG, Glasspool, R, Goode, EL, Goodman, MT, Grownwald, J, Harrington, P, Harter, P, Hasmad, HN, Hein, A, Heitz, F, Hildebrandt, MAT, Hillemanns, P, Hogdall, E, Hogdall, C, Hosono, S, Iversen, ES, Jakubowska, A, Jensen, A, Ji, B-T, Karlan, BY, Kellar, M, Kelley, JL, Kiemeney, LA, Krakstad, C, Kjaer, SK, Kupryjanczyk, J, Lambrechts, D, Lambrechts, S, Le, ND, Lee, AW, Lele, S, Leminen, A, Lester, J, Levine, DA, Liang, D, Lissowska, J, Lu, K, Lubinski, J, Lundvall, L, Massuger, LFAG, Matsuo, K, McGuire, V, McLaughlin, JR, McNeish, I, Menon, U, Modugno, F, Moes-Sosnowska, J, Moysich, KB, Narod, SA, Nedergaard, L, Ness, RB, Nevanlinna, H, Adenan, NAM, Odunsi, K, Olson, SH, Orlow, I, Orsulic, S, Weber, RP, Paul, J, Pearce, CL, Pejovic, T, Pelttari, LM, Permuth-Wey, J, Pike, MC, Poole, EM, Ramus, SJ, Risch, HA, Rosen, B, Rossing, MA, Rothstein, JH, Rudolph, A, Runnebaum, IB, Rzepecka, IK, Salvesen, HB, Schildkraut, JM, Schwaab, I, Shu, X-O, Shvetsov, YB, Siddiqui, N, Sieh, W, Song, H, Southey, MC, Sucheston, L, Tangen, IL, Teo, S-H, Terry, KL, Thompson, PJ, Tworoger, SS, van Altena, AM, Van Nieuwenhuysen, E, Vergote, I, Vierkant, RA, Wang-Gohrke, S, Walsh, C, Wentzensen, N, Whittemore, AS, Wicklund, KG, Wilkens, LR, Sawicki, W, Woo, Y-L, Wu, X, Wu, AH, Yang, H, Zheng, W, Ziogas, A, Sellers, TA, Freedman, ML, Chenevix-Trench, G, Pharoah, PDP, Gayther, SA, Berchuck, A   +160 more
openaire   +6 more sources

Rapid recurrence of a ruptured mucinous borderline ovarian tumor harboring K-RAS mutation followed by progression into anaplastic carcinoma with TP53 mutation

Heliyon, 2022
We describe the case of a young patient with a borderline mucinous ovarian tumor that progressed into ipsilateral ovarian anaplastic carcinoma in only 3 months with metastasis to the contralateral ovary and extensive spread in the pelvic and abdominal ...
Yang Yang, Yanxian Guan, Manman Xu, Junxiu Liu   +3 more
doaj   +1 more source

Primary Ovarian Mucinous Carcinoma with Signet Ring Cells – Report of A Rare Case [PDF]

Journal of Clinical and Diagnostic Research, 2014
Presence of signet ring cells in ovarian neoplasms are commonly encountered in Krukenberg tumours of ovary. Unusual presence in primary ovarian mucinous tumours may create a diagnostic difficulty.
Jaya Ganesh P, Vimal Chander R, Kanchana M P, Lakshmi Narasimhan   +3 more
doaj   +1 more source

Fertility-Sparing Surgery in Infiltrative Mucinous Carcinoma of the Ovary

Case Reports in Oncology, 2023
Introduction: Mucinous ovarian carcinoma is often diagnosed early and can affect young patients. The preservation of the female reproductive organ is one of the critical issues, especially for nulliparous women.
Sarra ben Ltaief, Montassar Ghalleb, Azza Chabchoub, Maher Slimen, Linda Hadj Kacem, Yosr Zenzeri, Riadh Chargui, Tarek Dhieb   +7 more
doaj   +1 more source

Preoperative serum levels of cancer antigen 125 and carcinoembryonic antigen ratio can improve differentiation between mucinous ovarian carcinoma and other epithelial ovarian carcinomas [PDF]

Obstetrics & Gynecology Science, 2018
ObjectiveThe main aim of this study was to evaluate cancer antigen 125 (CA125)/carcinoembryonic antigen (CEA) ratio (CCR), as a reliable marker to differentiate ovarian mucinous carcinoma from other epithelial ovarian carcinomas (EOCs), namely serous ...
Ji Hui Choi, Geum Seon Sohn, Doo Byung Chay, Han Byoul Cho, Jae-Hoon Kim   +4 more
doaj   +1 more source

Appendiceal tumors in patients undergoing primary surgery for mucinous ovarian tumors in a tertiary hospital, in Southern Thailand

Taiwanese Journal of Obstetrics & Gynecology, 2022
Objective: To evaluate the prevalence of appendiceal tumors in patients diagnosed with mucinous ovarian tumors and to determine factors associated with coexisting appendiceal tumors.
Kulisara Nanthamongkolkul, Panote Wattanapaisal, Sathana Boonyapipat, Yuthasak Suphasynth, Aroontorn Pichatechaiyoot, Alan Frederick Geater, Kanita Kayasut, Krantarat Peeyananjarassri   +7 more
doaj   +1 more source

Profiling the immune landscape in mucinous ovarian carcinoma [PDF]

Gynecologic Oncology, 2023
Mucinous ovarian carcinoma (MOC) is a rare histotype of ovarian cancer, with low response rates to standard chemotherapy, and very poor survival for patients diagnosed at advanced stage. There is a limited understanding of the MOC immune landscape, and consequently whether immune checkpoint inhibitors could be considered for a subset of patients.We ...
Meagher, NS, Hamilton, P, Milne, K, Thornton, S, Harris, B, Weir, A, Alsop, J, Bisinoto, C, Brenton, JD, Brooks-Wilsoni, A, Chiu, DS, Cushing-Haugen, KL, Fereday, S, Garsed, DW, Gayther, SA, Gentry-Maharaj, A, Gilks, B, Jimenez-Linan, M, Kennedy, CJ, Le, ND, Piskorz, AM, Riggan, MJ, Shah, M, Singh, N, Talhoukj, A, Widschwendter, M, Bowtell, DDL, dos Reis, FJC, Cook, LS, Fortner, RT, Garcia, MJ, Harris, HR, Huntsman, DG, Karnezis, AN, Kobel, M, Menon, U, Pharoah, PDP, Doherty, JA, Anglesioj, MS, Pike, MC, Pearce, CL, Friedlander, ML, DeFazio, A, Nelson, BH, Ramus, SJ   +44 more
openaire   +5 more sources

Targeting Src in Mucinous Ovarian Carcinoma [PDF]

Clinical Cancer Research, 2011
Abstract Purpose: Mucinous ovarian carcinomas have a distinct clinical pattern compared with other subtypes of ovarian carcinoma. Here, we evaluated (i) stage-specific clinical significance of mucinous ovarian carcinomas in a large cohort and (ii) the functional role of Src kinase in preclinical models of mucinous ovarian carcinoma.
Koji, Matsuo, Masato, Nishimura, Justin N, Bottsford-Miller, Jie, Huang, Kakajan, Komurov, Guillermo N, Armaiz-Pena, Mian M K, Shahzad, Rebecca L, Stone, Ju Won, Roh, Angela M, Sanguino, Chunhua, Lu, Dwight D, Im, Neil B, Rosenshien, Atsuko, Sakakibara, Tadayoshi, Nagano, Masato, Yamasaki, Takayuki, Enomoto, Tadashi, Kimura, Prahlad T, Ram, Kathleen M, Schmeler, Gary E, Gallick, Kwong K, Wong, Michael, Frumovitz, Anil K, Sood   +23 more
openaire   +2 more sources

A prognostic model of patients with ovarian mucinous adenocarcinoma: a population-based analysis

Journal of Ovarian Research, 2022
Background Ovarian mucinous carcinoma is a disease that requires unique treatment. But for a long time, guidelines for ovarian serous carcinoma have been used for the treatment of ovarian mucinous carcinoma.
Li Yang, Jinfen Yu, Shuang Zhang, Yisi Shan, Yajun Li, Liugang Xu, Jinhu Zhang, Jianya Zhang   +7 more
doaj   +1 more source

Recent Insights into Mucinous Ovarian Carcinoma [PDF]

International Journal of Molecular Sciences, 2018
Ovarian mucinous tumors represent a group of rare neoplasms with a still undefined cell of origin but with an apparent progression from benign to borderline to carcinoma. Even though these tumors are different from the other histological subtypes of epithelial ovarian neoplasms, they are still treated with a similar chemotherapeutic approach.
Ricci, Francesca, Affatato, Roberta, Carrassa, Laura, Damia, Giovanna   +3 more
openaire   +2 more sources