Results 51 to 60 of about 30,112 (235)

P53 and PIK3CA Mutations in KRAS/HER2 Negative Ovarian Intestinal-Type Mucinous Carcinoma Associated with Mature Teratoma

open access: yesCase Reports in Obstetrics and Gynecology, 2020
Primary ovarian intestinal-type mucinous carcinomas associated with mature teratoma are rare and represent less than 3% of all primary ovarian neoplasms. The molecular profile of these tumors is still controversial.
Sarah Bouri   +4 more
doaj   +1 more source

Mucinous Cystic Neoplasm of the Pancreas is Not an Aggressive Entity [PDF]

open access: yes, 2014
Objective: Mucinous cystic neoplasms (MCNs) of the pancreas have often been confused with intraductal papillary mucinous neoplasms. We evaluated the clinicopathologic characteristics, prevalence of cancer, and prognosis of a large series of well ...
Bassi, Claudio   +12 more
core   +1 more source

Mucinous epithelial ovarian carcinoma

open access: yesAnnals of Oncology, 2016
Mucinous tumours involving the ovary may be benign, borderline, or malignant. Malignant tumours may be primary or metastatic. Differentiation between primary and metastatic involvement of the ovary is critical for optimal patient management. Even among skilled pathologists, this distinction can be problematic, as can the distinction between borderline ...
openaire   +2 more sources

Promoter methylation and downregulated expression of the TBX15 gene in ovarian carcinoma. [PDF]

open access: yes, 2016
TBX15 is a gene involved in the development of mesodermal derivatives. As the ovaries and the female reproductive system are of mesodermal origin, the aim of the present study was to determine the methylation status of the TBX15 gene promoter and the ...
Alberti, L.   +9 more
core   +2 more sources

Ovarian Mature Cystic Teratoma Combined with Mucinous Boderline Tumor-A Case Report with Literature Review

open access: yesBioMedica, 2020
Mature ovarian cystic teratoma with co-existing mucinous borderline tumor is an extremely rare finding in literature. Here, we report a case of bilateral mature cystic teratoma of the ovary with mucinous borderline tumors and intraepithelial carcinoma in
Lixin Wang, Gang Chen, Jingui Jiang
doaj   +3 more sources

CK7+/CK20+/CDX2+ mucinous carcinoma, arising in a mature cystic teratoma of ovary, presenting with disseminated metastasis and pseudomyxoma peritonei

open access: yesIndian Journal of Pathology and Microbiology
Mucinous carcinomas arising within an ovarian dermoid tumor are rare. Most of the cases reported in the literature show morphological features resembling an appendiceal mucinous neoplasm.
Amit K. Adhya   +3 more
doaj   +1 more source

Controversies in the efficacy of adjuvant chemotherapy in different epithelial ovarian carcinoma histologies

open access: yesJournal of Oncological Sciences, 2019
Aim: In this retrospective study, the efficacy of adjuvant chemotherapy and its contribution to prognosis were investigated in patients diagnosed with different subgroups of ovarian carcinoma at stages 1–3.
Ece Esin   +5 more
doaj   +1 more source

The molecular origin and taxonomy of mucinous ovarian carcinoma [PDF]

open access: yesNature Communications, 2019
AbstractMucinous ovarian carcinoma (MOC) is a unique subtype of ovarian cancer with an uncertain etiology, including whether it genuinely arises at the ovary or is metastatic disease from other organs. In addition, the molecular drivers of invasive progression, high-grade and metastatic disease are poorly defined.
Dane Cheasley   +63 more
openaire   +5 more sources

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

open access: yesAdvanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann   +15 more
wiley   +1 more source

HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy

open access: yesBMC Cancer, 2009
Background The response rate of ovarian mucinous carcinomas to paclitaxel/carboplatin is low, prompting interest in targeted molecular therapies. We investigated HER2 expression and amplification, and the potential for trastuzumab therapy in this ...
Swenerton Kenneth D   +10 more
doaj   +1 more source

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