Therapeutic Management of Rare Primary Ovarian Neoplasms: Carcinosarcoma, Leiomyosarcoma, Melanoma and Carcinoid. [PDF]
Carcinosarcoma, leiomyosarcoma, melanoma and carcinoid as primary tumors in the ovary are extremely rare. In this paper, the authors reviewed the literature from 2010 to 2021, based on specific criteria, to analyze the treatment of these rare ovarian ...
Kozłowski M+3 more
europepmc +2 more sources
Use of tumor markers to distinguish endometriosis-related ovarian neoplasms from ovarian endometrioma. [PDF]
Objective Only few studies have focused on tumor markers used in the preoperative diagnosis of endometriosis-related ovarian neoplasms, and previous studies have only assessed serum CA125 levels.
Shinmura H+6 more
europepmc +2 more sources
VEGF Expression to Support Targeted Therapy in Ovarian Surface Epithelial Neoplasms [PDF]
Introduction: Vascular Endothelial Growth Factor (VEGF), a promoter of angiogenesis, is a promising target for antiangiogenic therapy in ovarian cancer.
Sudeshna Mukherjee+7 more
doaj +2 more sources
Aurora-A kinase is differentially expressed in the nucleus and cytoplasm in normal Müllerian epithelium and benign, borderline and malignant serous ovarian neoplasms [PDF]
Background Aurora-A kinase is important for cellular proliferation and is implicated in the tumorigenesis of several malignancies, including of the ovary. Information regarding the expression patterns of Aurora-A in normal Müllerian epithelium as well as
Khaled J. Alkhateeb+9 more
doaj +2 more sources
Stromal p16 expression is significantly increased in malignant ovarian neoplasms. [PDF]
Alterations in p16 protein expression have been reported to be associated with tumor development and progression. However, p16 expression status in the peritumoral stroma has been rarely investigated. We investigated the stromal p16 expression in ovarian
Yoon N, Yoon G, Park CK, Kim HS.
europepmc +2 more sources
Accuracy of intraoperative frozen section for the evaluation of ovarian neoplasms: an institutional experience. [PDF]
BackgroundOvarian neoplasms are a heterogeneous group of tumors including surface epithelial, germ cell and sex cord stromal tumors with a subset having low malignant potential (borderline tumors).
Hashmi AA+6 more
europepmc +2 more sources
Pregnancy Outcomes after Conservative Surgery for Early-Stage Ovarian Neoplasms [PDF]
Objective: This retrospective, single institute study aimed to evaluate pregnancy and oncologic outcomes in reproductive-age Thai women with early-stage ovarian neoplasms undergoing conservative surgical treatment. Methods: Medical records of 84 women of
Ratanasrithong P, Benjapibal M.
europepmc +2 more sources
Diffusion weighted imaging for the differential diagnosis of benign vs. malignant ovarian neoplasms. [PDF]
In order to assess the diagnostic accuracy of diffusion weighted imaging (DWI) in differentiating between benign and malignant ovarian neoplasms, a systemic meta-analysis was conducted. Relevant studies were retrieved from scientific literature databases,
Meng XF, Zhu SC, Sun SJ, Guo JC, Wang X.
europepmc +2 more sources
Multipoint Kras oncogene mutations potentially indicate mucinous carcinoma on the entire spectrum of mucinous ovarian neoplasms. [PDF]
Kras mutation is a common phenomenon in many human neoplasms. We aimed to assess the Kras mutational status along the histological continuum from normal ovaries to the development of benign, borderline and malignant ovarian mucinous neoplasms.
Lee YJ+7 more
europepmc +2 more sources
Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms [PDF]
BackgroundMucinous ovarian tumors represent a distinct histotype of epithelial ovarian cancer. The rarest (2-4 % of ovarian carcinomas) of the five major histotypes, their genomic landscape remains poorly described.
Robertson Mackenzie+17 more
openalex +2 more sources