Results 101 to 110 of about 553,624 (295)
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source
How is Nanoarchitectonics Shaping Extracellular Vesicle Research?
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake +5 more
wiley +1 more source
Proteomic analysis of cell models of ovarian cancer tumour suppression [PDF]
Epithelial ovarian cancer (EOC) is the most common form of gynaecological malignancy in the developed world. Identifying molecular markers of disease may provide novel approaches to screening and could enable targeted treatment and the design of novel
Sinclair, J.R.
core
Seromucinous Cystadenoma of Ovary – A Rare Case Report [PDF]
Ovarian epithelial tumours are common diseases of female genital tract, they account for the majority of female ovarian neoplasms. The recent World Health Organization (WHO) 2014 classification of tumours of female reproductive Organs introduced a new ...
Savitri M. Nerune +2 more
doaj
A prognostic model for ovarian neoplasms established by an integrated analysis of 1580 transcriptomic profiles. [PDF]
Hua Y +6 more
europepmc +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
A study of the predictive value of morphometric assessments in clinical outcome in ovarian epithelial malignancy [PDF]
Quantitative pathology as a tool in gynaecological pathology is fairly new. Such techniques allow greater objectivity than histological grading, typing, and residual tumour estimation.
Palmer, Julia Elizabeth
core
Clinical resistance to platinum chemotherapy in ovarian cancer [PDF]
Platinum drugs are the most active agents in ovarian cancer. Their cytotoxicty results from DNA crosslinking. High tumour response rates are seen, but 80 % of patients relapse. Major mechanisms of platinum resistance in patients remain to be established.
Newton, C., Newton, C
core

