Results 251 to 260 of about 819,375 (392)

Role of Intraoperative Frozen Section in the Diagnosis of Ovarian Neoplasms- A Retrospective Study in an Oncology Centre

, 2022
Nandyala Rukmangadha, Sai Chandana Gali, Amit Kumar Chowhan, Aruna Prayaga   +3 more
openalex   +1 more source

Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera

Advanced Science, EarlyView.
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang, Xinyu Qiu, Xiaoning Tong, Shaoju Gan, Weicheng Yi, Sitao Xie, Xiangsheng Liu, Chao Zuo, Weihong Tan   +8 more
wiley   +1 more source

Histomorphological Features of Ovarian Neoplasms and Expression of p53 and WT1 in Surface Epithelial Tumours: A Cross-sectional Study

, 2022
Nupur Kaushik, Deepa Selvi Rani, Shikha Prakash, Richa Singh, Lalit Kumar   +4 more
openalex   +1 more source

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang, Jiamin Wang, Guanjie Peng, Haichuan Zhang, Jinxin Fang, Yingyin Gao, Enzhe Lou, Yangzhou Liu, Wa Ding, Bingyuan Liu, Qiong Mao, Lizhen Jiang, Aochu Liu, Xinyue Li, Shiwen Hu, Qiaomin Ma, Yueyuan Zheng, Zhigang Zhao, Xianping Shi   +18 more
wiley   +1 more source

Pathogenesis and the Role of ARID1A Mutation in Endometriosis-related Ovarian Neoplasms

Advances in Anatomic Pathology, 2013
D. Maeda, I. Shih
semanticscholar   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

Evaluation of Ovarian Neoplasms in Honduras: Characteristics and Diagnostic Concordance Between Ultrasound, Tumor Markers and Histopathology. [PDF]

Gynecol Oncol Rep, 2019
Moon AS, Bourdeth A, Jerez R, Alger J, Chuang L.   +4 more
europepmc   +1 more source

Radiographic Features of a Benign Mixed Brenner Tumor and Mucinous Cystadenoma: A Rarely Identified Ovarian Neoplasm on Imaging

, 2020
Mitchell P. Wilson, Prayash Katlariwala, June H. K. Hwang, Gavin Low   +3 more
openalex   +1 more source

Study of immuno-histochemical markers ER, PR and Her2/neu in ovarian neoplasms

, 2022
Anjana Choudhary, Geeta Pachori, Vivek Mavaliya, Saroj Pachori   +3 more
openalex   +2 more sources

FOXL2 molecular testing in ovarian neoplasms: diagnostic approach and procedural guidelines

Modern Pathology, 2013
S. Kommoss, M. Anglesio, R. Mackenzie, Winnie Yang, J. Senz, Julie Ho, Lynda Bell, Sylvia Lee, Julie Lorette, D. Huntsman, C. Gilks   +10 more
semanticscholar   +1 more source