Results 281 to 290 of about 819,375 (392)
Novel quaternary ammonium salt‐linked STING agonist ADC demonstrates high potency, stability, enhanced solubility, and reduced off‐target toxicity, potently activating the STING pathway in the tumor microenvironment through the synergistic action of the Fab and Fc regions of antibodies (activity switch‐on) while exhibiting ≈20 fold lower activity in ...
Yu Long+17 more
wiley +1 more source
Detection of the HE4 protein in urine as a biomarker for ovarian neoplasms: Clinical correlates. [PDF]
Liao JB+5 more
europepmc +1 more source
The Role of Intraoperative Cytology in the Diagnostic Evaluation of Ovarian Neoplasms
M. Shahid+4 more
semanticscholar +1 more source
Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang+16 more
wiley +1 more source
Clinicopathologic features of ovarian neoplasms with emphasis on borderline ovarian tumors: an institutional perspective. [PDF]
Hashmi AA+6 more
europepmc +1 more source
Single‐cell RNA sequencing identifies MMP11⁺ CAFs as pro‐angiogenic cells accumulating during bladder cancer progression. These cells promote angiogenesis by regulating ESM1⁺ tip endothelial cells and recruiting SPP1⁺ macrophages. Tumor‐derived BMP2 promotes their activation.
Wuwu Xu+13 more
wiley +1 more source
Serum CA19.9 levels are commonly elevated in primary ovarian mucinous tumours but cannot be used to predict the histological subtype [PDF]
Archbold, Pooler+4 more
core +1 more source
This study presents an explainable multimodal AI model, MAIGGT (Multimodal Artificial Intelligence Germline Genetic Testing), that combines whole‐slide histopathology with clinical data for accurate germline BRCA1/2 mutation prescreening. By integrating digital pathology and EHR phenotypes, MAIGCT enables cost‐effective, scalable hereditary breast ...
Zijian Yang+23 more
wiley +1 more source