Results 111 to 120 of about 624,533 (255)

The influence of ovarian cyst type and size on ovarian reserve markers: implications for fertility counseling and preservation strategy

Frontiers in Endocrinology
BackgroundOvarian cysts are common in reproductive-aged women and may affect ovarian reserve, thereby impacting fertility potential. This study aimed to evaluate the differential impact of various ovarian cyst types and sizes on ovarian reserve markers ...
Xingyu Sun, Doudou Liu, Zijing Guo, Lijuan He, Shaohua Wang   +4 more
doaj   +1 more source

Diminished ovarian reserve in patients with psoriasis

, 2018
Objective: Psoriasis is a multi-systemic chronic inflammatory skin disease. Previous data suggests that women with some chronic inflammatory diseases have diminished ovarian reserve.
Elif Didem Özdemir, Ozdemir, Elif Didem, Aslıhan Alhan, Ayanoglu, Burcu Tugrul, Burcu Tuğrul Ayanoğlu, Onur Türkoğlu, Turkoglu, Onur, Alhan, Aslihan   +7 more
core   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Multi‐Layer Transcriptomic Comparison Across Human, Pig, and Mouse Informs Tissue‐ and Trait‐Specific Animal Model Selection

Advanced Science, EarlyView.
We integrated RNA‐seq data from humans, pigs, and mice across 15 matched tissues based on 14 910 one‐to‐one orthologous genes. Cross‐species similarity was systematically evaluated across multiple regulatory layers, including global co‐expression conservation, co‐expression networks, tissue‐specific programs, and 3D genome architecture.
Jingwen Dou, Yong Liao, Xiong Shen, Xin Huang, Zhenshuang Tang, Yuwei Gou, Huajun Zhou, Jingya Xu, Hong Liu, Yue Wang, Keke Liang, Jia Liu, Xiao Zhang, Chenyao Li, Shangjian Wang, Liangliang Fu, Lilin Yin, Xinyun Li, Shuhong Zhao, Xiaolei Liu, Jingjin Li, Yuhua Fu   +21 more
wiley   +1 more source

Cell-free DNA level in follicular fluid pools according to the patients’ ovarian reserve status, ovarian reserve parameters and infertility length.

, 2015
A, Follicular fluid cfDNA content in patients with normal ovarian reserve versus patients with ovarian reserve disorders (ovarian insufficiency and polycystic ovary syndrome); *p = 0.03.
Elodie Scalici (784922), Tal Anahory (784925), Tiffany Mullet (784923), Claire Vincens (784924), Samir Hamamah (156465), Sabine Traver (261020), Nicolas Molinari (75348)   +6 more
core   +1 more source

TROP2‐Targeting Chimeras (TRTACs) for Tumor Cell‐Selective Membrane Protein Degradation and Enhanced Drug Delivery

Advanced Science, EarlyView.
TROP2 is identified as a novel tumor‐selective lysosomal‐targeting receptor with established clinical relevance. TROP2‐targeting chimeras (TRTACs) are developed by genetically fusing a TROP2‐binding nanobody to nanobodies against specific target proteins.
Luping Chen, Xinying Fu, Wenqian Dong, Xiaobei Deng, Simin Chen, Fujun Wang, Jian Zhao, Shiqun Shao, Liqiang Fan, Jingyu Zhang, Lixin Zhang   +10 more
wiley   +1 more source

Application of endoluminal three-dimensional power Doppler in evaluation of ovarian reserve function after unilateral ovarian endometriotic cyst removal

肿瘤影像学, 2017
Objective: To explore the application of endoluminal three-dimensional power Doppler in evaluation of ovarian reserve function after unilateral ovarian endometriotic cyst removal.
ZHANG Ping, YING Tao, YAN Yulin, WANG Xia, DOU Chaoran, SHUI Wen, MA Li   +6 more
doaj  

Reduced pretreatment ovarian reserve in premenopausal female patients with Hodgkin lymphoma or non-Hodgkin-lymphoma--evaluation by using antimüllerian hormone and retrieved oocytes

, 2012
To study whether the ovarian reserve in female lymphoma patients is already reduced before the start of ...
Lawrenz, Barbara, Centers of FertiPROTEKT Network,, von Wolff, Michael, Henes, Joerg, Fehm, Tanja, Henes, Melanie, Soekler, Martin, Huebner, Stephanie, Centers of FertiPROTEKT Network   +8 more
core   +1 more source

Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception

Advanced Science, EarlyView.
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng, Ren‐Wang Peng, Chang‐Cheng Wu, Chi‐Wen Luo, Emmanuel Naveen Raj, Zhi‐Hong Wen, Tzu‐Hung Hsiao, Chia‐Jung Li   +7 more
wiley   +1 more source

Diminished ovarian reserve in systemic lupus erythematosus: clinical, immunological, viral, and therapeutic determinants in a 24-month prospective study

Frontiers in Immunology
Background and objectivesSystemic lupus erythematosus (SLE) predominantly affects women of reproductive age; however, the impact of the disease, chronic inflammation, and its treatments on ovarian reserve remains insufficiently characterized.
Margherita Rizzo, Margherita Rizzo, Silvia Beltrami, Francesca Ruffilli, Francesca Ruffilli, Carlo Garaffoni, Ettore Silvagni, Ettore Silvagni, Daria Bortolotti, Giorgia Cianci, Maila Galloppa, Beatrice Maranini, Marcello Govoni, Marcello Govoni, Roberta Rizzo, Alessandra Bortoluzzi, Alessandra Bortoluzzi   +16 more
doaj   +1 more source