Results 121 to 130 of about 32,628 (294)

Ovarian reserve in the dynamics of the girls-teenagers and young women after surgical treatment for benign ovarian disease

RUDN Journal of Medicine, 2012
It was done estimation the condition of ovarian reserve of 51 women 15—25 years old in dynamic after surgery and conservative treatment for benign non-inflammatory ovarian diseases, by identification of AMG level, ovarian volume and count of antral ...
T N Zulumyan, M B Khamoshina, V D Petrova, N D Plaksina, Z M Sochova, S D Semyatov   +5 more
doaj  

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

The influence of uterine artery embolisation on ovarian reserve, fertility, and pregnancy outcomes – a review of literature

, 2017
Uterine fibroids are considered to be the most frequent female benign tumours. Fibroids affect mainly women of reproductive age. The most frequently reported signs and symptoms of fibroids include disturbances of the menstrual cycle such as heavy ...
Paweł Milart, Sławomir Woźniak, Tomasz Paszkowski, Anna Stępniak, Wojciech Wrona, Piotr Czuczwar   +5 more
core   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Is ovarian reserve related to blood type?

Is ovarian reserve related to blood type? In recent years, several reports have pointed to a novel association between blood type ABO and a number of processes related to female infertility, including diminished ovarian reserve (DOR), poor response to ...
Bellver Pradas, José
core   +1 more source

Anti-Müllerian hormone versus antral follicle count as first-choice biomarkers in a low-resource setting: A cross-sectional study in Kumasi, Ghana

Journal of International Medical Research
Objective To evaluate age-related variations in ovarian reserve among women in Kumasi, Ghana, and determine the preferred first-choice biomarker, either anti-Müllerian hormone or antral follicle count, in a low-resource setting. Methods A cross-sectional
Francis Jojo Moses Kwadzo Damalie, Kweku Bedu-Addo, Charles Mawunyo Senaya, Edward Tieru Dassah, Alexander Anning, Phillip Kweku Baidoo, Kofi Owusu-Daaku, Patrick Addo-Fordjour   +7 more
doaj   +1 more source

Potential damage to the ovarian reserve during laparoscopic electrocoagulation of endometrioid cysts and benign ovarian cysts

Клинический разбор в общей медицине
Introduction. Endometrioid ovarian cysts (endometriomas) are one of the most common clinical manifestations of endometriosis with a prevalence of 17 to 44% in the population.
Anastasia E. Averyanova, Shanmugaraj Kulanthaivel, Lada A. Alekseeva, Daniil A. Sokur, Ekaterina I. Tkachenko, Elizaveta A. Derbunova, Varvara S. Murashova   +6 more
doaj   +1 more source