Results 141 to 150 of about 581,549 (298)

Ovarian Reserve

open access: yes, 2020
Nidhi Sharma, Sudakshina Chakrabarti
openaire   +2 more sources

Federal reserve bulletin /

open access: yes, 1915
Title from cover.Mode of access: Internet.Vols. for -2005 issued by: Board of Governors of the Federal Reserve System.Index-digest, v. 1 (1914)-6 (1920).
United States. Federal Reserve Board.   +1 more
core  

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang   +14 more
wiley   +1 more source

Corynoxine Inhibits Tumor Growth via Targeting NQO1 and Modulating the PTPA–NQO1/PP2A Switch to Activate PP2A

open access: yesAdvanced Science, EarlyView.
Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou   +6 more
wiley   +1 more source

Integrative Management of Acupuncture for Diminished Ovarian Reserve with Insomnia: Study Protocol for a Prospective Randomized Controlled Trial [PDF]

open access: yes
Yuanyuan Lai,1,* Dan Chen,1,* Chunhui Tian,1 Yufei Huang,1 Di Gan,1,2 Liying Liu,1 Jie Yang1,3 1Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of ...
Lai Y   +6 more
core  

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang   +5 more
wiley   +1 more source

Federal reserve inter-district collection system /

open access: yes
Description based on: June 1, 1917."Changes in list of banks upon which items will be received by federal reserve banks for collection and credit" (varies slightly).Mode of access: Internet.Issued 1916-1935 by the Federal Reserve Board; issued 1936 ...
United States. Federal Reserve Board.   +1 more
core  

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

open access: yesAdvanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy