Results 151 to 160 of about 26,707 (256)

Association between menstrual cycle length and ovarian reserve markers and stimulation response: a retrospective cohort study. [PDF]

BMC Womens Health
Aykanat G, Ertan B, Kalkan FT, Atlıhan U, Acet F, Goker ENT, Tavmergen E.   +6 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Nicotinamide Reverses the Warburg Effect in CHO Cell Culture

Biotechnology and Bioengineering, EarlyView.
Abstract The Warburg effect, the preferential conversion of glucose‐derived pyruvat to lactate despite available oxygen, is a key feature of Chinese hamster ovary (CHO) cell culture. Lactate accumulation in recombinant protein‐producing cell culture is an inefficient usage of glucose, as well as being deleterious to cells.
James Morrissey, Ayca Cankorur‐Cetinkaya, Luigi Grassi, Annie J. Harwood‐Stamper, Jonathan Welsh, Ryte Poskute, Kasia Kozakowska‐McDonnell, Cleo Kontoravdi   +7 more
wiley   +1 more source

Mesenchymal Stem Cell-Derived Exosomes for Ovarian Reserve: A Systematic Review and Network Meta‑Analysis Based on Animal Studies. [PDF]

Stem Cell Rev Rep
Yu M, Ma Y, Sun X, Zhao J, Sun T, Tang L.   +5 more
europepmc   +1 more source

Detergent Virus Inactivation in Chromatography Systems

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Detergent treatment is a widely utilized virus‐inactivation step in therapeutic protein manufacturing to safeguard products. Traditionally, this operation is performed in an incubation vessel in batch mode. In this investigation, a methodology was developed to enable virus inactivation via a post‐load, detergent‐containing wash within a bind ...
Kang Cai, Etienne Utiger, Chris Afdahl, Rayan Zamat, Jennifer Anderson, Yeldys De Armas, Gisela Ferreira   +6 more
wiley   +1 more source

IVF Outcomes After PPOS Versus Flexible GnRH-Antagonist Protocol in Advanced-Age Women With Diminished Ovarian Reserve: A Retrospective Study. [PDF]

Health Sci Rep
Zhang J, Bai L, Wang S, Yu C, Wang X, Zhou J, Hu L, Chen L, Hu H.   +8 more
europepmc   +1 more source

Ginsenoside Rb2 improves diminished ovarian reserve through regulation of gonadal hormones and apoptosis via SIRT1. [PDF]

J Ovarian Res
Zhu C, Yi M, Cao H, Li H, Tang H, Xu L, Li L.   +6 more
europepmc   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Associations between daytime napping and parameters of ovarian reserve among women undergoing assisted reproductive technology. [PDF]

BMC Womens Health
Hou QQ, Liao HM, Tian WQ, Yao QY, Qin DY, Yuan XQ, Yao W, Du YY, Li J, Wang Y, Zeng Q, Deng TR, Liu C, Li YF.   +13 more
europepmc   +1 more source