Results 61 to 70 of about 61,342 (328)

Association between thyroid-associated antibodies and ovarian reserve in infertile women: a clinical study of 526 cases

陆军军医大学学报
Objective To compare the positive rate of thyroid autoantibodies in infertile women with different ovarian reserve function, and investigate the immune factors of diminished ovarian reserve.
BU Xiaomeng, BU Xiaomeng, LIU Yanjun, LIU Yanjun   +3 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Laparoscopic guided minilaparotomy: a modified technique for management of benign large ovarian cysts

BMC Women's Health, 2022
Background The aim of the study is to evaluate the efficiency and safety of a novel technique to treat large benign ovarian cysts combining benefits of laparoscopic management along with mini-laparotomy without affection of the ovarian reserve.
Mohamed F. Shaltout, Ahmed M. Maged, Rana Abdella, Mona M. Sediek, Sherif Dahab, Moutaz M. Elsherbini, Rasha O. Elkomy, Sherif Sameh Zaki   +7 more
doaj   +1 more source

Apoptosis in mouse fetal and neonatal oocytes during meiotic prophase one [PDF]

, 2007
Background The vast majority of oocytes formed in the fetal ovary do not survive beyond birth. Possible reasons for their loss include the elimination of non-viable genetic constitutions arising through meiosis, however, the ...
Ghafari , Fataneh, Gutierrez , Carlos G., Hartshorne, Geraldine M.   +2 more
core   +4 more sources

Association of ABO blood groups with ovarian reserve: a retrospective cohort study in Chinese Han women younger than 40 years with infertility

Journal of Ovarian Research, 2022
Background Ovarian reserve reflects both the quantity and quality of oocytes available for procreation and is affected by many known and unknown factors.
Xingyu Sun, Chenyu Sun, Muzi Meng, Ling Liu   +3 more
doaj   +1 more source

Neonatal exposure to xenoestrogens impairs the ovarian response to gonadotropin treatment in lambs [PDF]

, 2015
Bisphenol A (BPA) and diethylstilbestrol (DES) are xenoestrogens which have been associated with altered effects on reproduction. We hypothesized that neonatal xenoestrogen exposure affects the ovarian functionality in lambs.
Belmonte, Norberto Miguel, Bosquiazzo, Veronica Lis, Luque, Enrique Hugo, Muñoz de Toro, Monica Milagros, Osti, Mario, Rivera, Oscar E., Rodriguez, Horacio Adolfo, Santamaría, Clarisa Guillermina, Varayoud, Jorgelina Guadalupe   +8 more
core   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Anti-müllerian hormone levels and antral follicle count in women with a BRCA1 or BRCA2 germline pathogenic variant: A retrospective cohort study

Breast, 2021
Background: Some studies suggested a decreased ovarian reserve among BRCA1/2 pathogenic variant carriers, with conflicting results. Methods: We conducted a retrospective single-center observational study of ovarian reserve and spontaneous fertility ...
Laurie Denis-Laroque, Youenn Drouet, Ingrid Plotton, Nicolas Chopin, Valérie Bonadona, Jacqueline Lornage, Bruno Salle, Christine Lasset, Christine Rousset-Jablonski   +8 more
doaj   +1 more source

SEASONAL INCIDENCE OF CAPTURE AND REPRODUCTION OF FIVE FOSSORIAL SNAKE SPECIES IN WEST VIRGINIA [PDF]

, 2017
Museum specimens of five species of fossorial snakes collected in West Virginia during 1930–2000 were examined to determine monthly incidence of capture, adult body sizes, reproductive cycle, and clutch characteristics.
Herrick, Kelli-Marie, Meshaka, Walter E., Pauley, Thomas K., Wright, Danielle F.   +3 more
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source