Results 41 to 50 of about 624,533 (255)

Association between thyroid-associated antibodies and ovarian reserve in infertile women: a clinical study of 526 cases

陆军军医大学学报
Objective To compare the positive rate of thyroid autoantibodies in infertile women with different ovarian reserve function, and investigate the immune factors of diminished ovarian reserve.
BU Xiaomeng, BU Xiaomeng, LIU Yanjun, LIU Yanjun   +3 more
doaj   +1 more source

Characterization of micro-RNA in women with different ovarian reserve

Scientific Reports, 2021
Women undergoing infertility treatment are routinely subjected to one or more tests of ovarian reserve. Therefore, an adequate assessment of the ovarian reserve is necessary for the treatment. In this study, we aimed to characterize the potential role of
Masood Abu-Halima, Lea Simone Becker, Basim M. Ayesh, Simona Lucia Baus, Amer Hamza, Ulrike Fischer, Mohamad Hammadeh, Andreas Keller, Eckart Meese   +8 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Comparative study of assisted reproductive outcomes between young patients with occult premature ovarian insufficiency and advanced-age patients

Journal of International Medical Research, 2020
Objective The purpose of this study was to compare the pregnancy outcomes among young patients with occult premature ovarian insufficiency (OPOI), advanced-age patients with diminished ovarian reserve (DOR), and advanced-age patients with normal ovarian ...
Ling-nv Yao, Wen-qin Lin, Nan Jiang, Chuyan Li, Hai-feng Cao, Hong Li, Jian-hua Qian   +6 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

IMPACT OF LAPAROSCOPIC OVARIAN CYSTECTOMY VERSUS LAPAROSCOPIC COAGULATION ON OVARIAN RESERVE IN CASES OF OVARIAN ENDOMETRIOMA [PDF]

Zagazig University Medical Journal, 2017
Objectives: To compare between laparoscopic ovarian cystectomy and laparoscopic ovarian coagulation on ovarian reserve in cases of ovarian endometrioma.
Yousry Shalal, Youssef ElSayed, Mohamed Mahdy, Mohamed Zaitoun   +3 more
doaj   +1 more source

Epigenetic programming in the ovarian reserve [PDF]

, 2023
The ovarian reserve defines female reproductive lifespan, which in humans spans decades. The ovarian reserve consists of oocytes residing in primordial follicles arrested in meiotic prophase I and is maintained independent of DNA replication and cell ...
Mengwen Hu, Richard M. Schultz, Satoshi H. Namekawa, Schultz, Richard M, Namekawa, Satoshi H, Hu, Mengwen   +5 more
core   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Ovarian reserve

, 2005
The tendency to delay childbirth has increased the importance of ovarian reserve as a determinant of infertility treatment outcome. In the context of assisted reproduction technology, effective strategies to overcome the impact of ovarian aging and ...
Fauser, BCJM, Fauser, B C J M, Macklon, NS, Macklon, N.S.   +3 more
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source