Results 61 to 70 of about 581,549 (298)

Incomplete pregnancy and risk of ovarian cancer: Results from two Australian case–control studies and systematic review [PDF]

, 2009
Although full-term pregnancies reduce the risk of ovarian cancer, it has not been conclusively established whether incomplete pregnancies also influence risk.
Dick, Marie-Louise B., Purdie, David M., Dick, Marie Louise B, Green, Adele C., The Australian Ovarian Cancer Study Group, Siskind, Vic, Siskind, Victor, Australian Cancer Study Group (Ovarian Group)   +7 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Ovarian reserve and endometrioid ovarian cysts: Clinical and ultrasound aspects

, 2020
The objective. To study laparoscopic values and establish specificities of endometrioid ovarian cysts and Doppler parameters in healthy ovarian tissue containing an endometrioid cyst in infertile patients with low and normal ovarian reserve. Patients and
Gasparov A.S., Dutov A.A., Lapteva N.V., Pyatykh N.S., Dubinskaya E.D.   +4 more
core   +2 more sources

Ovarian reserve in women with endometriosis under total cystectomy compared to partial cystectomy: A randomized clinical trial

International Journal of Reproductive BioMedicine, 2021
Background: The standard procedure for ovarian endometriosis is laparoscopic excision of ovarian cysts and complete removal of the cyst capsule using the striping technique.
Atiye Javaheri, Samane Kabirpour Ashkezar, Maryam Eftekhar, Seiede Zahra Ghanadzade Tafti   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Risk factors for diminished ovarian reserve in women: Current state of the problem

Acta Biomedica Scientifica
Ovarian reserve is the basis of female fertility. The main markers of ovarian reserve are the level of anti-Mullerian hormone and the number of antral follicles.
S. V. Zotov, V. V. Likhacheva, P. Yu. Motyreva, O. V. Azarova, B. I. Ayzikovich   +4 more
doaj   +1 more source

A validated model of serum Anti-Müllerian hormone from conception to menopause [PDF]

, 2011
<p><b>Background:</b> Anti-Mullerian hormone (AMH) is a product of growing ovarian follicles. The concentration of AMH in blood may also reflect the non-growing follicle (NGF) population, i.e.
Kelsey, Tom, Richard A. Anderson, W. Hamish B Wallace, Wallace, W Hamish B, Thomas W. Kelsey, Phoebe Wright, Wright, P., Nelson, Scott M, Wallace, W.H.B., Nelson, S.M., Anderson, Richard, Scott M. Nelson, Thomas W Kelsey, Richard A Anderson, W Hamish B Wallace, Anderson, Richard A, Wallace, Hamish, Anderson, R.A., Wright, Phoebe, Nelson, Scott, Kelsey, Thomas W, Kelsey, T.W., Scott M Nelson   +22 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Laparoscopic guided minilaparotomy: a modified technique for management of benign large ovarian cysts

BMC Women's Health, 2022
Background The aim of the study is to evaluate the efficiency and safety of a novel technique to treat large benign ovarian cysts combining benefits of laparoscopic management along with mini-laparotomy without affection of the ovarian reserve.
Mohamed F. Shaltout, Ahmed M. Maged, Rana Abdella, Mona M. Sediek, Sherif Dahab, Moutaz M. Elsherbini, Rasha O. Elkomy, Sherif Sameh Zaki   +7 more
doaj   +1 more source