Results 111 to 120 of about 5,855,418 (301)

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Pseudocolouring Enhancement Processing Of Ovarian Ultrasound Images. [PDF]

, 2003
Image processing may be employed on ovarian ultrasound images to assist doctors in diagnostic ...
Mashor, Mohd Yusoff, Ngah, Umi Kalthum, Saidin, Nafiza   +2 more
core   +1 more source

Role of follicle-stimulating hormone receptor polymorphism in predicting ovarian response to letrozole in women with polycystic ovary syndrome during ovulation induction

Frontiers in Endocrinology
BackgroundLetrozole is a first-line treatment for anovulatory infertility in women with polycystic ovary syndrome (PCOS). Despite its widespread use, a significant proportion of patients exhibit non-responsive cycles, limiting treatment efficacy ...
Xiuxian Zhu, Xiuxian Zhu, Xiuxian Zhu, Qiaoling Wang, Qiaoling Wang, Jingwen Lang, Jingwen Lang, Yunqing Zhi, Yunqing Zhi, Yonglun Fu, Yonglun Fu, Shihua Bao, Shihua Bao   +12 more
doaj   +1 more source

Pretreatment anti-Müllerian hormone predicts for loss of ovarian function after chemotherapy for early breast cancer [PDF]

, 2013
Aim: Improving survival for women with early breast cancer (eBC) requires greater attention to the consequences of treatment, including risk to ovarian function. We have assessed whether biochemical markers of the ovarian reserve might improve prediction
Anderson, Richard A., Kelsey, Tom, Rosendahl, Mikkel, Kelsey, Thomas W., Anderson, Richard, Cameron, David A., Cameron, David, Kelsey, Tom; id_orcid   +7 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Sensitivity and Specificity of Measuring Anti-Müllerian Hormone and Follicle Stimulating Hormone levels in Predicting Response to Ovarian Stimulation in Infertile Women [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Background and Objective: Assisted reproductive technologies (ART), including in vitro fertilization (IVF) and embryo transfer, have achieved considerable success, largely due to controlled ovarian hyperstimulation (COH).
B Jabir Edan, H Mahdi Kadhim, H Resheed Behayaa   +2 more
doaj  

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Age of women and the number of antral follicles in predicting ovarian response in intrauterine insemination (IUI)

Caspian Journal of Reproductive Medicine, 2015
Background: Fertility specialists assess ovarian responses prior to estimating the prognosis for women who are suffering from anovulation. To diagnose the inconsistencies between chronological and biological age of ovaries and predict ovarian response ...
Zahra Basirat, Masoumeh Golsorkhtabaramiri   +1 more
doaj   +2 more sources