Results 61 to 70 of about 934,351 (287)

The role of the growth hormone in assisted reproductive technologies cycles [PDF]

Гинекология, 2019
The paper analyzes the literature data on the use of the growth hormone (GH) in ovarian stimulation in assisted reproductive technologies (ART). Routine use of GH in ovarian stimulation in patients with a normal GH level does not increase pregnancy and ...
Andrey Y Romanov, Anastasiya G Syrkasheva, Nataliya V Dolgushina, Elena A Kalinina   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Investigating the potential for expediting diagnosis of ovarian cancer via prompt symptom recognition & "targeted screening" [PDF]

, 2009
PhDThis thesis explores the potential for using symptoms as a tool to bring forward the diagnosis of ovarian cancer. Current evidence supports the existence of prediagnostic symptoms, however symptom lead time has yet to be adequately quantified ...
Lim, Anita Wey Wey
core   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

ESHRE guideline on ovarian stimulation for IVF/ICSI – 2025

Репродуктивная эндокринология
The aim of the ovarian stimulation guideline is to provide clinicians with evidence-based information on the different options for ovarian stimulation for in vitro fertilization (IVF) / intracytoplasmic sperm injection (ICSI), taking into account issues ...
REPRODUCTIVE ENDOCRINOLOGY
doaj   +1 more source

Ovarian volume throughout life : a validated normative model [PDF]

, 2013
The measurement of ovarian volume has been shown to be a useful indirect indicator of the ovarian reserve in women of reproductive age, in the diagnosis and management of a number of disorders of puberty and adult reproductive function, and is under ...
Dodwell, Sarah, Wilkinson, A Graham, Sarah K. Dodwell, Andersen, Claus, Wallace, W Hamish B, Claus Y Andersen, Thomas W Kelsey, Richard A Anderson, Wallace, Hamish, Andersen, Claus Y, Wilkinson A. Graham, Dodwell, Sarah K, Wallace W. Hamish B, Andersen Claus Y., A Graham Wilkinson, Kelsey, Thomas W, Kelsey, Tom, Richard A. Anderson, Dodwell Sarah K., Greve, Tine, W. Hamish B Wallace, Thomas W. Kelsey, Claus Y. Andersen, Kelsey Thomas W., Anderson, Richard, Tine Greve, W Hamish B Wallace, Greve Tine, Anderson Richard A., Anderson, Richard A, Sarah K Dodwell, Wilkinson, Graham, A. Graham Wilkinson   +32 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Individualized controlled ovarian stimulation in expected poor-responders: an update

Reproductive Biology and Endocrinology, 2018
Controlled ovarian stimulation with subsequent multi-follicular development continues to be a keystone in ART. Evidence supports an individualized approach to ovarian stimulation, usually involving combinations of ovarian reserve tests, body mass index ...
Thor Haahr, Sandro C. Esteves, Peter Humaidan   +2 more
doaj   +1 more source

Erratum: ESHRE guideline: ovarian stimulation for IVF/ICSI [PDF]

, 2020
[This corrects the article DOI: 10.1093/hropen/hoaa009.][This corrects the article DOI: 10.1093/hropen/hoaa009.]
ESHRE Guideline Group on Ovarian Stimulation
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source