Results 1 to 10 of about 3,722,377 (405)
Purpose Resident memory CD8 T cells, owing to their ability to reside and persist in peripheral tissues, impart adaptive sentinel activity and amplify local immune response, and have beneficial implications for tumor surveillance and control. The current
Wenjun He +12 more
doaj +2 more sources
Tumor Microenvironment in Ovarian Cancer: Function and Therapeutic Strategy
Ovarian cancer is one of the leading causes of death in patients with gynecological malignancy. Despite optimal cytoreductive surgery and platinum-based chemotherapy, ovarian cancer disseminates and relapses frequently, with poor prognosis.
Yanfei Yang +4 more
doaj +2 more sources
Background Patients with giant ovarian tumor often have severe symptoms, such as abdominal distention, and the tumor tends to grow rapidly; therefore, sufficient preoperative assessments are difficult to perform.
Yoshiaki Maeda +4 more
doaj +1 more source
Ovarian Leydig cell tumor is a rare type of ovarian steroid cell neoplasms, presenting in only 0.1% of all ovarian tumor cases, and is generally androgen-secreting and unilateral.
Diana Bužinskienė +3 more
doaj +1 more source
Giant ovarian tumors are rare, as most cases are diagnosed during routine gynecological check-ups or abdominal ultrasound examinations. They are a challenge for gynecologists and surgeons. Diagnosis in such patients is difficult due to the limitations of the medical apparatus. Perioperative management requires specialized anesthetic medical care and is
Tomasz Kluz +4 more
openaire +3 more sources
Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. [PDF]
Autophagy, particularly with BECN1, has paradoxically been highlighted as tumor promoting in Ras-driven cancers, but potentially tumor suppressing in breast and ovarian cancers.
Axelrod, Joshua +14 more
core +1 more source
Ovarian dermoid cysts are a common benign tumor. Although there is often a genetic component to this abnormality, this report discusses the case of a patient with an ovarian dermoid tumor with no family history of gynecological cancer. The diagnosis, surgical management, and malignancy of ovarian dermoid cysts are discussed.
St. Louis, Mya +4 more
openaire +2 more sources
Background and Objectives: Ovarian cancer is the leading cause of death among gynecological tumors. PD-1/PD-L1 immunoregulatory mechanism is activated in ovarian cancers. Lymphocyte infiltration is a significant factor that affects its expression.
Ljubiša Jovanović +6 more
doaj +1 more source
Overexpression of EFEMP1 correlates with tumor progression and poor prognosis in human ovarian carcinoma. [PDF]
OBJECTIVE:This study was to explore the role of EFEMP1 in ovarian tumor progression and its relationship with prognosis of ovarian carcinoma. METHODS:EFEMP1 mRNA and protein expressions in normal ovarian tissue, ovarian tumor, high invasive subclones and
Jie Chen +4 more
doaj +1 more source
Aim: We sought to determine the epidemiology of mucinous ovarian tumors, the correlation between serum biomarkers and tumor status, and the outcomes of the management in different subtypes of mucinous ovarian tumors in a Chinese surgical cohort. Methods:
Yuanyuan Zhang PhD +8 more
doaj +1 more source

