Results 11 to 20 of about 3,722,377 (405)

Driving Immune Responses in the Ovarian Tumor Microenvironment

open access: yesFrontiers in Oncology, 2021
Ovarian cancer is the leading cause of death among gynecological neoplasms, with an estimated 14,000 deaths in 2019. First-line treatment options center around a taxane and platinum-based chemotherapy regimen. However, many patients often have recurrence
Franklin Ning, C. B. Cole, C. Annunziata
semanticscholar   +1 more source

Metagenomic Analysis of Serum Microbe-Derived Extracellular Vesicles and Diagnostic Models to Differentiate Ovarian Cancer and Benign Ovarian Tumor

open access: yesCancers, 2020
We aimed to develop a diagnostic model identifying ovarian cancer (OC) from benign ovarian tumors using metagenomic data from serum microbe-derived extracellular vesicles (EVs). We obtained serum samples from 166 patients with pathologically confirmed OC
S. I. Kim   +10 more
semanticscholar   +1 more source

Oncolytic adenovirus shapes the ovarian tumor microenvironment for potent tumor-infiltrating lymphocyte tumor reactivity

open access: yesJournal for ImmunoTherapy of Cancer, 2020
Background Ovarian cancers often contain significant numbers of tumor-infiltrating lymphocytes (TILs) that can be readily harnessed for adoptive T-cell therapy (ACT).
Joao M Santos   +11 more
semanticscholar   +1 more source

Tumor-Associated Macrophages and Ovarian Cancer: Implications for Therapy

open access: yesCancers, 2022
Simple Summary Ovarian cancer is a highly lethal female malignancy with high rates of advanced stage and recurrent disease. Ovarian cancer is characterized as poorly responsive to immunotherapy.
D. Schweer   +5 more
semanticscholar   +1 more source

Active Delivery of VLPs Promotes Anti-Tumor Activity in a Mouse Ovarian Tumor Model.

open access: yesSmall, 2020
Virus-like nanoparticles (VLPs) have been used as an attractive means in cancer immunotherapy because of their unique intrinsic immunostimulatory properties.
Chao Wang   +7 more
semanticscholar   +1 more source

Biodegradable Mg Implants Suppress the Growth of Ovarian Tumor.

open access: yesACS Biomaterials Science & Engineering, 2020
The common treatment of epithelial ovarian cancer is aggressive surgery followed by platinum-based cytotoxic chemotherapy. However, residual tumor cells are resistant to chemotherapeutic drugs during postoperative recurrence.
S. Qiao   +10 more
semanticscholar   +1 more source

Primary ovarian carcinoid arising in associated mature cystic teratoma

open access: yesBMC Women's Health, 2022
Background Primary ovarian carcinoid is a very rare ovarian low-grade neuroendocrine tumor, accounting for about 0.1% of all ovarian neoplasms. Case presentation We reported a case of primary ovarian carcinoid arising from a mature cystic teratoma in a ...
Wanyu Zhang, Qiongrong Chen
doaj   +1 more source

HER2/Neu Expression was Different between Benign, Borderline and Malignant Epithelial Ovarian Tumors

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2014
Objective: To determine the difference of HER2/neu expression in benign, borderline and malignant epithelial ovarian tumor. Method: An analytic cross-sectional study was performed on 49 samples of epithelial ovarian cases which were divided into three
Yona S. Hadisubroto, Ketut Suwiyoga
doaj   +1 more source

Exosomes promote pre-metastatic niche formation in ovarian cancer. [PDF]

open access: yes, 2019
Ovarian cancer is one of the most common gynecological malignancies. Upon initial diagnosis, the majority of patients present with widespread metastatic growth within the peritoneal cavity. This metastatic growth occurs in stages, with the formation of a
Dean, Dylan C   +4 more
core   +2 more sources

HE4 in the differential diagnosis of ovarian masses [PDF]

open access: yes, 2015
Ovarian masses, a common finding among pre- and post-menopausal women, can be benign or malignant. Ovarian cancer is the leading cause of death from gynecologic malignancy among women living in industrialized countries.
ANASTASI, Emanuela   +5 more
core   +1 more source

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