Results 211 to 220 of about 3,722,377 (405)

Supplementary Figure 2 from miR-450a Acts as a Tumor Suppressor in Ovarian Cancer by Regulating Energy Metabolism

, 2023
Bruna Rodrigues Muys, Josane F. Sousa, Jéssica Rodrigues Plaça, Luíza Ferreira de Araújo, Aishe A. Sarshad, Dimitrios G. Anastasakis, Xiantao Wang, Xiao Ling Li, Greice Andreotti de Molfetta, Anelisa Ramão, Ashish Lal, Daniel Onofre Vidal, Markus Hafner, Wilson A. Silva   +13 more
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Visfatin increases the invasive potential of ovarian granulosa tumor spheroids by reprogramming glucose metabolism [PDF]

, 2023
Justyna Gogola-Mruk, Weronika Marynowicz, Kinga Krawczyk, Anna Ptak   +3 more
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Pulmonary thromboembolism secondary to pelvic thrombosis related to giant ovarian tumor [PDF]

, 2019
Alberto Amadasi, S Andreola, Marta Bianchi, Michele Boracchi, Guendalina Gentile, Francesca Maciocco, Matteo Marchesi, Riccardo Zoja   +7 more
openalex   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Characterization of tumor-infiltrating lymphocytes in ovarian cancer and development of a peptide-based anti-cancer vaccine

, 2017
Kevin Röhle
openalex   +1 more source

Positive Feedback Loop of Histone Lactylation‐Driven HNRNPC Promotes Autophagy to Confer Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance

Advanced Science, EarlyView.
Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang, Jiao Chen, En‐Liang Zhu, Ming‐Jian Ma, Yang‐Yin‐Hui Yu, Ying‐Qin Zhu, Jing‐Yuan Ye, Jin‐Zhao Xie, Zi‐Yi Zhao, Xiao‐Yu Yin   +9 more
wiley   +1 more source

<p>CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway</p>

, 2020
Yi-Han Bai, Kemin Yin, Tong Su, Fang Ji, Shu Zhang   +4 more
openalex   +2 more sources

OP17.06: Triage for surgical management of ovarian tumors in symptomatic women: Assessment of an ultrasound‐based scoring system [PDF]

, 2008
J. L. Alcázar, Pedro Royo, R. Galván, C. Laparte, Manuel García-Manero, José Ángel Mínguez, Martina Arribas Jurado, Guillermo López García   +7 more
openalex   +1 more source