Results 231 to 240 of about 3,722,377 (405)

Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth.

Cancer Research, 2016
Yu-Hung Huang, W. Peng, N. Furuuchi, J. Gerhart, Kelly R Rhodes, N. Mukherjee, M. Jimbo, G. Gonye, J. Brody, R. Getts, J. Sawicki   +10 more
semanticscholar   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

The Ultrasonography Characteristics of Borderline Ovarian Tumor Subtypes. [PDF]

J Ultrasound Med
Yoeli-Bik R, Lengyel E, Timor-Tritsch IE, Kurnit K, Puiu S, Longman RE, Abramowicz JS.   +6 more
europepmc   +1 more source

New Drug Updates in Solid Tumors: PARP Inhibitors in Ovarian Cancer, Immunotherapeutics, and Other Agents

, 2018
Li, Edward
openalex   +2 more sources

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Large Mucinous Borderline Ovarian Tumor in an Asymptomatic Woman: A Case Report. [PDF]

Cureus
Troupi M, Koliopoulos S, Shihada A, Samolis A, Chrysikos D, Troupis T.   +5 more
europepmc   +1 more source

Supplementary Figure 3 from Frequent Loss of <i>NISCH</i> Promotes Tumor Proliferation and Invasion in Ovarian Cancer via Inhibiting the FAK Signal Pathway

, 2023
Jing Li, Xiaoying He, Ruofan Dong, Yuan Wang, Jinjin Yu, Haifeng Qiu   +5 more
openalex   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

Advanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao, Qian Hao, Yu Gan, Jing Tong, Xiaodan Chen, Shuran Tan, Ruiwen Ruan, Yingdan Huang, Mingming Cao, Jun Deng, Tao Han, Getao Shi, Bo Gao, Yu Zhang, Xiang Zhou   +14 more
wiley   +1 more source

Ovarian Tumor Biomarkers: Correlation Between Tumor Type and Marker Expression, and Their Role in Guiding Therapeutic Strategies. [PDF]

Int J Mol Sci
Gawełczyk W, Soczyńska J, Muzyka A, Rydzek J, Majcherczyk K, Żołyniak M, Woźniak S.   +6 more
europepmc   +1 more source

LOH at 6q and 10q in fractionated circulating DNA of ovarian cancer patients is predictive for tumor cell spread and overall survival [PDF]

, 2012
Jan Dominik Kuhlmann, Heidi Schwarzenbach, Pauline Wimberger, Micaela Poetsch, Rainer Kimmig, Sabine Kasimir‐Bauer   +5 more
openalex   +1 more source