Results 241 to 250 of about 3,722,377 (405)

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source

Early-fusion hybrid CNN-transformer models for multiclass ovarian tumor ultrasound classification. [PDF]

Front Artif Intell
Garcia-Atutxa I, Martínez-Más J, Bueno-Crespo A, Villanueva-Flores F.   +3 more
europepmc   +1 more source

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

Advanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li, Dong Zhang, Eryu Peng, Shijun Shen, Hamid Alinejad‐Rokny, Yao Liu, Junke Zheng, Cizhong Jiang, Youqiong Ye   +8 more
wiley   +1 more source

Borderline Ovarian Tumor Recurrence after Two Decades: The Importance of Long-term Surveillance. [PDF]

Gynecol Minim Invasive Ther
Shih WC, Li PC, Ding DC.
europepmc   +1 more source

HLA-A2 presents shared tumor-associated antigens derived from endogenous proteins in ovarian cancer. [PDF]

, 1993
George E. Peoples, P S Goedegebuure, John Andrews, Deric D. Schoof, Timothy J. Eberlein   +4 more
openalex   +1 more source

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

Advanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang, Zhengna Zhu, Hongju Yang, Yaping Yan, Luyao Ran, Naixue Yang, Yichao Wang, Li Wu, Bing Bai, Weizhi Ji, Wei Si   +10 more
wiley   +1 more source

Overlap MCAP-CLAPO syndrome associated with malignant ovarian tumor in a 11 year old girl. [PDF]

JAAD Case Rep
Cerro Rodríguez DD, Losada JDP, Lista FS, Pola SG, Tellado MG.   +4 more
europepmc   +1 more source

Characterizing the tumor microenvironment of metastatic ovarian cancer by single cell transcriptomics [PDF]

, 2020
Susan Olalekan, Bingqing Xie, Rebecca Back, Heather Eckart, Anindita Basu   +4 more
openalex   +1 more source

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

Nature Medicine, 2011
K. Nieman, H. Kenny, Carla V. Penicka, A. Ladányi, R. Buell-Gutbrod, M. Zillhardt, Iris L. Romero, Mark S Carey, Gordon B Mills, G. Hotamisligil, S. Yamada, Marcus E Peter, K. Gwin, E. Lengyel   +13 more
semanticscholar   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source