Results 171 to 180 of about 1,349,645 (219)
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Skeletal alterations in ovariectomized rats

Calcified Tissue International, 1985
Female Sprague Dawley rats were subjected to either bilateral ovariectomy or sham surgery. Tetracycline derivatives were administered to each rat on two separate occasions to label sites of bone formation. All rats were sacrificed at 5 weeks postovariectomy and their proximal tibiae were processed undecalcified for quantitative bone histomorphometry. A
T J, Wronski   +3 more
openaire   +2 more sources

Hyperviscosity syndrome in ovariectomized rats

Bulletin of Experimental Biology and Medicine, 2008
Ovariectomy reduces blood levels of sex hormones and considerably increases blood viscosity due to an increase in hematocrit and plasma fibrinogen content, disorders in viscoelastic characteristics of erythrocytes, and increase of their aggregation activity.
A M, Plotnikova   +4 more
openaire   +2 more sources

Incadronate inhibits osteoporosis in ovariectomized rats

European Journal of Pharmacology, 2002
Incadronate is a highly effective inhibitor of stimulated bone resorption as demonstrated in a hypercalcemia model in rats, bone metastasis models in mice and rats, and an osteoporosis model in dogs. In this study, the effect of incadronate on osteoporosis in ovariectomized rats was examined.
Kyoko, Teramura   +5 more
openaire   +2 more sources

Estradiol–sertraline synergy in ovariectomized rats

Psychoneuroendocrinology, 2008
This study investigated estradiol (E(2)) modulation of the antidepressant effects of a selective serotonin (5-HT) reuptake inhibitor (SSRI; sertraline) and a tricyclic antidepressant (imipramine) as measured by the forced swim test (FST) followed by assessment of gene and protein expression for the 5-HT transporter (SERT) and multiple 5-HT receptors ...
Stacy L, Sell   +5 more
openaire   +2 more sources

Biomechanical evaluation in osteoporosis: ovariectomized rat model

Clinical Rheumatology, 2006
The aim of our study was to investigate the effects of ovariectomy on rat femur biomechanical parameters. Bone mineral density (BMD) and histological investigation were also evaluated. Fourteen female Sprague-Dawley rats (seven ovariectomized, seven control) were used. BMD was measured by dual-energy X-ray absorbsiometry.
Ulku, Comelekoglu   +7 more
openaire   +2 more sources

Skeletal Effects of Calcitonin in Ovariectomized Rats*

Endocrinology, 1991
Although calcitonin (CT) has been shown to be effective for the prevention of bone loss in early postmenopausal women, the skeletal effects of the hormone specifically during the early stages of estrogen deficiency have not been characterized histomorphometrically to date.
T J, Wronski   +6 more
openaire   +2 more sources

Placenta Hominis Protects Osteoporosis in Ovariectomized Rats

Immunopharmacology and Immunotoxicology, 2006
In China, Japan, and Korea, placenta hominis extracts (PHEs) are used clinically for the treatment of osteoporosis. The anti-osteoporotic effect of PHEs was studied. The trabecular bone area and thickness in OVX rats decreased by 50% from those in sham-operated rats; these decreases were completely inhibited by administration of PHEs for 7 weeks ...
H J, Chae   +11 more
openaire   +2 more sources

Kaempferitrin prevents bone lost in ovariectomized rats

Phytomedicine, 2015
Podocarpium podocarpum (DC.), an edible and medicinal plant popularly used for the treatment of bruises and fracture in Chinese folk medicine, has been proved to possess significant antiosteoporotic effect in our latest research.Our study aimed to investigate the in vitro and in vivo antiosteoporotic effect of kaempfertrin (KN), a principal flavonoid ...
Xue-Qin, Ma   +6 more
openaire   +2 more sources

Thermal analysis of bones from ovariectomized rats

Journal of Biomedical Materials Research, 1998
Thermal analyses [thermogravimetry (TG) and differential thermal analysis (DTA)], X-ray diffraction, and infrared absorption analysis of bones from ovariectomized rats were carried out. The rats were divided into five groups: sham operated (Sham); ovariectomized (OVX); OVX given traditional Chinese (Kampo) medicine, Unkei-to; OVX given 17 beta ...
Y, Okamoto   +5 more
openaire   +2 more sources

Cardiovascular Effect of Diosgenin in Ovariectomized Rats

Journal of Medicinal Food, 2019
Diosgenin is a phytoestrogen and a constituent of Dioscorea. It has several biological effects, and some of them are anti-inflammatory, antidiabetic, antitumor, and vasodilatory. The present study investigated both the vasorelaxing and antioxidant mechanisms of diosgenin in isolated rat aortic rings.
Ilmara Cecilia Pinheiro de Silva, Morais   +9 more
openaire   +2 more sources

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