Results 171 to 180 of about 1,349,645 (219)
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Skeletal alterations in ovariectomized rats
Calcified Tissue International, 1985Female Sprague Dawley rats were subjected to either bilateral ovariectomy or sham surgery. Tetracycline derivatives were administered to each rat on two separate occasions to label sites of bone formation. All rats were sacrificed at 5 weeks postovariectomy and their proximal tibiae were processed undecalcified for quantitative bone histomorphometry. A
T J, Wronski +3 more
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Hyperviscosity syndrome in ovariectomized rats
Bulletin of Experimental Biology and Medicine, 2008Ovariectomy reduces blood levels of sex hormones and considerably increases blood viscosity due to an increase in hematocrit and plasma fibrinogen content, disorders in viscoelastic characteristics of erythrocytes, and increase of their aggregation activity.
A M, Plotnikova +4 more
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Incadronate inhibits osteoporosis in ovariectomized rats
European Journal of Pharmacology, 2002Incadronate is a highly effective inhibitor of stimulated bone resorption as demonstrated in a hypercalcemia model in rats, bone metastasis models in mice and rats, and an osteoporosis model in dogs. In this study, the effect of incadronate on osteoporosis in ovariectomized rats was examined.
Kyoko, Teramura +5 more
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Estradiol–sertraline synergy in ovariectomized rats
Psychoneuroendocrinology, 2008This study investigated estradiol (E(2)) modulation of the antidepressant effects of a selective serotonin (5-HT) reuptake inhibitor (SSRI; sertraline) and a tricyclic antidepressant (imipramine) as measured by the forced swim test (FST) followed by assessment of gene and protein expression for the 5-HT transporter (SERT) and multiple 5-HT receptors ...
Stacy L, Sell +5 more
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Biomechanical evaluation in osteoporosis: ovariectomized rat model
Clinical Rheumatology, 2006The aim of our study was to investigate the effects of ovariectomy on rat femur biomechanical parameters. Bone mineral density (BMD) and histological investigation were also evaluated. Fourteen female Sprague-Dawley rats (seven ovariectomized, seven control) were used. BMD was measured by dual-energy X-ray absorbsiometry.
Ulku, Comelekoglu +7 more
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Skeletal Effects of Calcitonin in Ovariectomized Rats*
Endocrinology, 1991Although calcitonin (CT) has been shown to be effective for the prevention of bone loss in early postmenopausal women, the skeletal effects of the hormone specifically during the early stages of estrogen deficiency have not been characterized histomorphometrically to date.
T J, Wronski +6 more
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Placenta Hominis Protects Osteoporosis in Ovariectomized Rats
Immunopharmacology and Immunotoxicology, 2006In China, Japan, and Korea, placenta hominis extracts (PHEs) are used clinically for the treatment of osteoporosis. The anti-osteoporotic effect of PHEs was studied. The trabecular bone area and thickness in OVX rats decreased by 50% from those in sham-operated rats; these decreases were completely inhibited by administration of PHEs for 7 weeks ...
H J, Chae +11 more
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Kaempferitrin prevents bone lost in ovariectomized rats
Phytomedicine, 2015Podocarpium podocarpum (DC.), an edible and medicinal plant popularly used for the treatment of bruises and fracture in Chinese folk medicine, has been proved to possess significant antiosteoporotic effect in our latest research.Our study aimed to investigate the in vitro and in vivo antiosteoporotic effect of kaempfertrin (KN), a principal flavonoid ...
Xue-Qin, Ma +6 more
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Thermal analysis of bones from ovariectomized rats
Journal of Biomedical Materials Research, 1998Thermal analyses [thermogravimetry (TG) and differential thermal analysis (DTA)], X-ray diffraction, and infrared absorption analysis of bones from ovariectomized rats were carried out. The rats were divided into five groups: sham operated (Sham); ovariectomized (OVX); OVX given traditional Chinese (Kampo) medicine, Unkei-to; OVX given 17 beta ...
Y, Okamoto +5 more
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Cardiovascular Effect of Diosgenin in Ovariectomized Rats
Journal of Medicinal Food, 2019Diosgenin is a phytoestrogen and a constituent of Dioscorea. It has several biological effects, and some of them are anti-inflammatory, antidiabetic, antitumor, and vasodilatory. The present study investigated both the vasorelaxing and antioxidant mechanisms of diosgenin in isolated rat aortic rings.
Ilmara Cecilia Pinheiro de Silva, Morais +9 more
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