Results 61 to 70 of about 1,349,645 (219)
Status epilepticus: Updates on mechanisms and treatments
Epilepsia Open, EarlyView.Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley +1 more source
Expression of melanocortin-4 receptor and agouti-related peptide mRNAs in arcuate nucleus during long term malnutrition of female ovariectomized rats [PDF]
Iranian Journal of Basic Medical Sciences, 2015 Objective: Melanocortin-4 receptor (MC4R) and agouti-related peptide (AgRP) are involved in energy homeostasis in the rat. The aim of the present study was to evaluate the expression of MC4R and AgRP mRNAs in arcuate nucleus (ARC) during long term ...
Fatemeh Sabet Sarvestani +7 more
doaj
BMC Medical Genomics, 2008 Background Vaginal atrophy (VA) is the thinning of the vaginal epithelial lining, typically the result of lowered estrogen levels during menopause. Some of the consequences of VA include increased susceptibility to bacterial infection, pain during sexual
Peano Bryan J +11 more
doaj +1 more source
Characteristics of an ovariectomized osteopenic rat model
Journal of Bone and Mineral Research, 1989 Abstract Although osteoporosis induced by ovariectomy (Ovx) in the rat has been widely used as a model for postmenopausal osteoporosis in humans, the findings of different investigators are not always consistent. This might be mainly due to differences in the age of the animals at Ovx, time after Ovx, and the variables measured ...
I, Yamazaki, H, Yamaguchi
openaire +2 more sources
MicroRNA expression profiling in an ovariectomized rat model of postmenopausal osteoporosis before and after estrogen treatment. [PDF]
Am J Transl Res, 2020 Xu X +7 more
europepmc +2 more sources
Molecular Medicine, 2022 Probucol (PBC) is a potent cholesterol-lowering drug and has been studied extensively for its powerful antioxidative stress. The purpose of this study is to investigate the role of PBC in ovariectomized rat model and to explore the mechanism of ...
Zhou-Shan Tao, Tian-Lin Li, Shan Wei
doaj +1 more source
Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats [PDF]
Toxicology and Applied Pharmacology, 2007 Given the tremendous importance of mitochondria to basic cellular functions as well as the critical role of mitochondrial impairment in a vast number of disorders, a compelling question is whether 17beta-estradiol (E2) modulates mitochondrial function. To answer this question we exposed isolated liver mitochondria to E2.
Moreira, Paula I. +6 more
openaire +3 more sources
Spine Surgery and Related Research, 2018 Introduction: Osteoporosis can produce a persistent state of pain known as osteoporotic pain. One proposed mechanism of this pathology is increased calcitonin gene-related peptide (CGRP; a marker related to inflammatory pain) expression in the dorsal ...
Sumihisa Orita +21 more
doaj +1 more source
Estrogenic Potential of Flemingia vestita Benth Tubers in Ovariectomized Rat Model
, 2016 Objective: This study investigates the potential estrogenic activity of the ethanolic extract of Flemingia vestita Benth tubers using ovariectomized rat model. Materials and Methods: The ethanolic extract of F.
S. Shailajan +5 more
semanticscholar +1 more source
The Ovariectomized Rat as a Model for Studying Alveolar Bone Loss in Postmenopausal Women
BioMed Research International, 2015 In postmenopausal women, reduced bone mineral density at the hip and spine is associated with an increased risk of tooth loss, possibly due to a loss of alveolar bone.
B. Johnston, W. Ward
semanticscholar +1 more source