Results 71 to 80 of about 1,357,718 (252)

Nanoparticle‐Based Tetracycline Delivery Systems: Advancing Therapeutic Effectiveness and Tackling Antibiotic Resistance

Particle &Particle Systems Characterization, EarlyView.
This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr, Mehrab Pourmadadi, Fatemeh Yazdian, Hamid Rashedi, Abbas Rahdar, M. Ali Aboudzadeh   +5 more
wiley   +1 more source

Estrous behavior in dairy cows: identification of underlying mechanisms and gene functions [PDF]

, 2010
Selection in dairy cattle for a higher milk yield has coincided with declined fertility. One of the factors is reduced expression of estrous behavior. Changes in systems that regulate the estrous behavior could be manifested by altered gene expression ...
Beerda, B., Boer, H.M.T., Veerkamp, R.F., Woelders, H.   +3 more
core   +2 more sources

Effects of Dietary Equol on the Pituitary of the Ovariectomized Rats

Hormone and Metabolic Research, 2007
The aim of our study was to evaluate the effects of dietary equol, metabolite of a phytoestrogen daidzein, on the secretion of prolactin (PRL) and lutenizing hormone (LH), as well as the expression of estrogen receptors (ERalpha, ERbeta and truncated estrogen receptor-1 (TERP-1) in the pituitary gland of ovariectomized (ovx) female Sprague-Dawley rats.
Rachon, Dominik, Vortherms, Tina, Seidlova-Wuttke, Dana, Wuttke, Wolfgang   +3 more
openaire   +4 more sources

Ovariectomized rats as a model of postmenopausal osteoarthritis: validation and application [PDF]

Arthritis Res Ther, 2004
We aimed to assess the effect of ovariectomy on cartilage turnover and degradation, to evaluate whether ovariectomized (OVX) rats could form an experimental model of postmenopausal osteoarthritis. The effect of ovariectomy on cartilage was studied using two cohorts of female Sprague-Dawley rats, aged 5 and 7 months.
Høegh-Andersen, Pernille, Tankó, László B, Andersen, Thomas L, Lundberg, Carina V, Mo, John A, Heegaard, Anne-Marie, Delaissé, Jean-Marie, Christgau, Stephan   +7 more
openaire   +4 more sources

Emerging Nanonutraceuticals against Obesity

Small Science, EarlyView.
This overview comprehensively compiles the latest research advancements in diversiform nanonutraceuticals against obesity. These nanonutraceuticals are derived from the nanomodifications of some carbohydrates, lipids, proteins, vitamins, minerals, and phytochemicals.
Linjie Ni, Minmin Peng, Yiying Liang, Xiwen Ye, Hanying Zheng, Dongbei Guo, Liang Yang, Xusangni Li, Ronghe Chen   +8 more
wiley   +1 more source

Biomechanical effects of menopause in ovariectomized rats’ femurs

Gynecological Endocrinology, 2013
To demonstrate the biomechanical changes in rat bones occurred by surgical menopause and to search for correlation between biomechanical test results and bone mineral density (BMD) measurements.Thirty female Wistar-albino rats aged ∼6 months and weighed ∼250-300 g were randomized into ovariectomy, sham and control groups.
Aksakal, Bunyamin, Kavak, Servet, Guner, Savas, Alkis, Ismet, OKYAY, AYŞE GÜLER, Turktas, Ugur   +5 more
openaire   +5 more sources

Bisphenol A Induces Neuronal Apoptosis and Oxidative Stress Through TRPV4 Channel Signaling Pathways: Protective Role of Alpha‐Lipoic Acid

Environmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), an environmental toxin, exerts adverse effects by increasing mitochondrial (mROS) and intracellular (iROS) reactive oxygen species, apoptosis, and Ca2+ influx in neurological diseases. However, antioxidants can mitigate these detrimental effects. This study aimed to investigate the protective role of antioxidant alpha‐lipoic
Ramazan Çinar, Mustafa Nazıroğlu
wiley   +1 more source

Comparison of chemical profiles and effectiveness between Erxian decoction and mixtures of decoctions of its individual herbs : a novel approach for identification of the standard chemicals [PDF]

, 2017
Acknowledgements This study was partially supported by grants from the Seed Funding Programme for Basic Research (Project Number 201211159146 and 201411159213), the University of Hong Kong.
Cheung, H. P., Chung, F. W. S., Lao, L. X., Ng, T. B., Sze, S. C. W., Tong, Y., Wang, S. W., Zhang, Y. B., Zhang, Z. J.   +8 more
core   +1 more source

Preventive Effect of Crocin on Osteoporosis in an Ovariectomized Rat Model

Evidence-Based Complementary and Alternative Medicine, 2014
The purpose of this study was to investigate the therapeutic effects of crocin on ovariectomy-induced osteoporosis in rats. Female Sprague-Dawley rats were randomly assigned to a sham-operated group (sham) and five ovariectomy (OVX) subgroups, that is ...
Peng-chong Cao, Wen-Xing Xiao, Ya-Bo Yan, Xiong Zhao, Shuai Liu, Jing-Qiao Feng, Wei Zhang, Jun Wang, Ya-fei Feng, Wei Lei   +9 more
semanticscholar   +1 more source

Nigella Sativa reverses osteoporosis in ovariectomized rats [PDF]

BMC Complementary and Alternative Medicine, 2014
Osteoporosis poses a significant public health issue. It is a skeletal disorder characterized by compromised bone strength that predisposes to increased risk of fracture. There is a direct relationship between the lack of estrogen after menopause and the development of osteoporosis.
openaire   +3 more sources