This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li +12 more
wiley +1 more source
BRCA1 alleviates inflammation, oxidative stress, and ovarian granulosa cell apoptosis by inhibiting endoplasmic reticulum stress, thereby ameliorating polycystic ovary syndrome. [PDF]
Huang X +7 more
europepmc +1 more source
Visium (no probes) data from the ovary (left) of a 19-year-old white female
J. Kim +7 more
openalex +1 more source
Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang +12 more
wiley +1 more source
Diverse impacts of aging on insulin resistance in lean and obese women with polycystic ovary syndrome: evidence from 1345 women with the syndrome [PDF]
Sarantis Livadas +3 more
openalex +1 more source
Immune Predictors of Radiotherapy Outcomes in Cervical Cancer
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang +8 more
wiley +1 more source
Contrasting La Crosse Virus Lineage III Vector Competency in Two Geographical Populations of <i>Aedes triseriatus</i> and <i>Aedes albopictus</i> Mosquitoes. [PDF]
Faw LR +3 more
europepmc +1 more source
Hyperandrogenism and metabolic disorders among women with polycystic ovary syndrome
Rubén González Tabares +5 more
openalex +1 more source
Effects of Metabolic Syndrome on Pregnancy Outcomes in Women Without Polycystic Ovary Syndrome [PDF]
Siyuan Li +3 more
openalex +1 more source

