Results 221 to 230 of about 325,405 (336)

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Functional Integration of Different-Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis. [PDF]

Adv Biol (Weinh)
Pfau DR, Rionda MA, Cho E, Clark JG, Kruger RE, Chan-Sui RK, Padmanabhan V, Moravek MB, Shikanov A.   +8 more
europepmc   +1 more source

The Fruits of Conservatism in the Treatment of Ovarian Pathology [PDF]

, 1959
Christian, Howard J.
core   +1 more source

Long-interval masculinizing Krukenberg tumor of the ovary

, 1982
A. Schoenfeld, Michael Pistiner, Silvio Pitlik, Joseph B. Rosenfeld, Jardena Ovadia   +4 more
openalex   +1 more source

Author response: Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism

, 2020
Krystal A. Orlando, Amber K Douglas, Aierken Abudu, Yemin Wang, Basile Tessier‐Cloutier, Weiping Su, Alec Peters, Larry S. Sherman, Rayvon Moore, Vinh Nguyen, Gian Luca Negri, Shane Colborne, Gregg B. Morin, Friedrich Kommoss, Jessica D. Lang, William P.D. Hendricks, Elizabeth A. Raupach, Patrick Pirrotte, David G. Huntsman, Jeffrey M. Trent, Joel S. Parker, Jesse R. Raab, Bernard E. Weissman   +22 more
openalex   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

Advanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao, Qian Hao, Yu Gan, Jing Tong, Xiaodan Chen, Shuran Tan, Ruiwen Ruan, Yingdan Huang, Mingming Cao, Jun Deng, Tao Han, Getao Shi, Bo Gao, Yu Zhang, Xiang Zhou   +14 more
wiley   +1 more source

Dynamic alternative polyadenylation in ovaries of Muscovy ducks across different laying stages based on full-length transcriptomics. [PDF]

Poult Sci
Niu Y, Yang X, Wang Y, Zhu L, Hu Z, Wang X.   +5 more
europepmc   +1 more source

A CASE OF CHOLANGIO CELL CARCINOMA WITH METASTASIS TO THE OVARY

, 2005
Yutaka Abe, Hiromichi Machida, Eiichi Hirai, Hiroshi Toda, Shingo Kameoka   +4 more
openalex   +2 more sources

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source

An mTOR-Stat3-Stathmin pathway controls centrosome and microtubule dynamics for oocyte polarization.

Curr Biol
Shawahny A, Bogoch Y, Hart N, Elkouby YM.   +3 more
europepmc   +1 more source