Results 171 to 180 of about 293,743 (295)
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma+18 more
wiley +1 more source
On the occurrence of compensatory hypertrophy in the ovary
E. S. Carmichael, F. H. A. Marshall
openalex +2 more sources
Primary and Secondary Carcinoma of the Ovary: A Statistical Record from the Pathological Institute of the London Hospital [PDF]
Gordon Ley
openalex +1 more source
Based on IP‐MS analysis, BAG2 is confirmed to be essential for ubiquitination and protein homeostasis regulation of STING in cervical cancer. BAG2 inhibits the ubiquitination and degradation of STING by forming a complex with STUB1, thereby activating the type I IFN signaling pathway and inhibiting the development of cervical cancer.
Shijie Yao+6 more
wiley +1 more source
Investigation of serum agouti-related peptide levels in women with polycystic ovary syndrome. [PDF]
Kırılmaz G, Kale İ.
europepmc +1 more source
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang+10 more
wiley +1 more source
Cellular distribution of estrogen receptors alpha in the rabbit ovary during pregnancy and lactation. [PDF]
Abd-Elkareem M+4 more
europepmc +1 more source
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi+20 more
wiley +1 more source