British Journal of Cancer, 2003 We report our experience in the management of patients with carcinosarcoma of the ovary, a rare but aggressive variant of ovarian cancer. Forty patients were treated at a single centre, which is the largest reported series. The median age at diagnosis was 65 years (range 45-86) and the median Karnofsky performance (KP) status was 70.
Harris, M. A. +10 more
openaire +3 more sources
Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration. [PDF]
, 2016 The new concept of mammalian sex maintenance establishes that particular key genes must remain active in the differentiated gonads to avoid genetic sex reprogramming, as described in adult ovaries after Foxl2 ablation.
Bakkali, Mohammed +9 more
core +2 more sources
Journal of the Endocrine Society, 2019 Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by hyperandrogenism and chronic anovulation. Depending on diagnostic criteria, 6% to 20% of reproductive aged women are affected.
S. Witchel, S. Oberfield, A. Pena
semanticscholar +1 more source
Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]
, 2016 This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia +4 more
core +2 more sources
Foliculogénesis Ovárica en la Raya Marmorada, Sympterygia bonapartii (Müller & Henle, 1841) (Chondrichthyes, Rajidae) [PDF]
, 2011 Los Condrictios se han convertido en un recurso económico importante en las últimas décadas, siendo Argentina uno de los países que más explota tiburones y rayas, incluso a niveles que exceden los límites de varias especies.
Díaz Andrade, María Constanza +3 more
core +1 more source
Increased expression of circulating miRNA-93 in women with polycystic ovary syndrome may represent a novel, non-invasive biomarker for diagnosis [PDF]
, 2015 MicroRNAs (miRNA) are a novel class of small noncoding single-stranded RNA molecules that regulate gene expression. There is increasing evidence of their importance in polycystic ovary syndrome (PCOS). The objective was to determine if miRNA-93 and miRNA-
Atkin, S. L. +3 more
core +1 more source
Leptin receptor in the chicken ovary: potential involvement in ovarian dysfunction of ad libitum-fed broiler breeder hens [PDF]
, 2004 In hens, the ovarian follicles committed to ovulation are arranged in an ordered follicular hierarchy. In standard broiler breeders hens genetically selected for high growth rate the reproductive function is clearly dysfunctional.
Cassy, Sandrine +5 more
core +3 more sources
Aging Cell, 2020 Fibrosis is a hallmark of aging tissues which often leads to altered architecture and function. The ovary is the first organ to show overt signs of aging, including increased fibrosis in the ovarian stroma.
F. Amargant +14 more
semanticscholar +1 more source
Association between circulating adiponectin levels and polycystic ovarian syndrome [PDF]
, 2014 Background: Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to insulin resistance (
Khan, Naveed Ali +4 more
core +3 more sources
Neuromuscular organization and aminergic modulation of contractions in the Drosophila ovary [PDF]
, 2006 Background: The processes by which eggs develop in the insect ovary are well characterized. Despite a large number of Drosophila mutants that cannot lay eggs, the way that the egg is moved along the reproductive tract from ovary to uterus is less well ...
Elliott, C.J.H. +5 more
core +3 more sources