Results 41 to 50 of about 293,743 (295)

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

The Role of m6A on Female Reproduction and Fertility: From Gonad Development to Ovarian Aging

Frontiers in Cell and Developmental Biology, 2022
The growth and maturation of oocyte is accompanied by the accumulation of abundant RNAs and posttranscriptional regulation. N6-methyladenosine (m6A) is the most prevalent epigenetic modification in mRNA, and precisely regulates the RNA metabolism as well
Xiaoyan Sun, Jiafeng Lu, Hong Li, Boxian Huang   +3 more
doaj   +1 more source

MENSTRUATION AND THE OVARIES. [PDF]

The Lancet, 1888
n ...
Aveling, JamesH, Campbell, Harry
openaire   +3 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Ovarian Fibrothecoma in a Holstein cow: A Case report [PDF]

The Iranian Journal of Veterinary Science and Technology, 2017
A 5-year-old Holstein cow was referred to the Veterinary Medicine Hospital, Urmia University, Urmia, Iran, with abnormal estrous cycle. At rectal palpation, the unilateral ovary enlargement was detected.
Ali Soleimanzadeh, RoozAli Batavani, Alireza Nourian, Belal Pashaie   +3 more
doaj   +1 more source

Immunohistological features of the collagen formation in ovaries of fetuses from mothers with a physiological pregnancy on different gestational terms

Journal of Education, Health and Sport, 2022
The comprehensive study on the fetal ovaries allowed us to disclose main features of the collagen synthesis in different organ’s components relatively to the gestational term of fetus.
L. Kupriianova, S. Ivanchenko
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Age, reproduction, and fecundity of a population of Cobitis sp. (Actinopterygii: Cypriniformes: Cobitidae) from the Babolrud River in the southern Caspian Sea basin [PDF]

Acta Ichthyologica et Piscatoria, 2011
Background. Loach fishes, Cobitis sp., are found in the majority of streams in the southern Caspian Sea basin, but reproductive parameters of them are barely known.
H. Mousavi Sabet, A. Kamali, M. Soltani, A. Bani, H.R. Esmaeili, H. Rostami, S. Vatandoust, Z. Moradkhani   +7 more
doaj   +3 more sources

Ovary transcriptomic analysis reveals regulation effects of dietary fish oil on hormone, lipid, and glucose metabolism in female adult spotted scat (Scatophagus argus)

Frontiers in Marine Science, 2022
In the aquaculture industry, fish oil is widely used as a nutritional supplement to promote the gonadal maturation of broodstocks, while the mechanism of fish oil on ovary development remain unclear.
Tuo Wang, Zhi-Long Liu, Guang-Li Li, Umar Farouk Mustapha, Charles Brighton Ndandala, Hong-Juan Shi, Chun-Hua Zhu, Chun-Hua Zhu, Hua-Pu Chen, Yang Huang, Dong-Neng Jiang   +10 more
doaj   +1 more source