Results 41 to 50 of about 748,294 (339)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Ovarian growth and ovulation in the mature blue crab, Callinectes sapidus Rathbun [PDF]
, 1942 Introduction. Observations: structure of the ovary during the periods of growth and ovulation in the mature crab (stages 1-5).
Hard, W.L.
core
Verhuellia is a segregate lineage in Piperaceae: more evidence from flower, fruit and pollen morphology, anatomy and development [PDF]
, 2010 Background and Aims The perianthless Piperales, i.e. Saururaceae and Piperaceae, have simple reduced flowers strikingly different from the other families of the order (e.g. Aristolochiaceae).
Goetghebeur, Paul +7 more
core +3 more sources
Obesity and Polycystic Ovary Syndrome: Implications for Pathogenesis and Novel Management Strategies
Clinical Medicine Insights: Reproductive Health, 2019 Polycystic ovary syndrome (PCOS) is a common female condition typified by reproductive, hyperandrogenic, and metabolic features. Polycystic ovary syndrome is a genetic condition, exacerbated by obesity.
T. Barber +3 more
semanticscholar +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Studies on the Helminth Fauna of Japan. Part 49. Cestodes of Fishes, II. [PDF]
, 1952 Caryophyllaeidae Claus, 1879 1. Glaridacris limnodrili Yamaguti, 1934 Bothriocephalidae Blanchard, 1849 2. Bothriocephalus fluviatilis n. sp. 3. B. lateolabracis n. sp. 4. B. branchiostegi n. sp. 5. B. acheilognathi Yamaguti, 1934 6. B. brotulae n. sp. 7.
Yamaguti, Satyu
core +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats [PDF]
, 2012 We investigated the effects of different windows of testosterone propionate (TP) treatment during foetal and neonatal life in female rats to determine whether and when excess androgen exposure would cause disruption of adult reproductive function ...
Abbott +50 more
core +3 more sources