Results 51 to 60 of about 748,294 (339)

Polycystic ovary syndrome [PDF]

open access: yesMedicine, 1989
This case illustrates the very common endocrine problem of polycystic ovary syndrome (PCOS). The diagnosis was not clear initially because of the absence of clinical evidence of androgen excess and of a normal random serum luteinizing hormone (LH) concentration.
openaire   +11 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Expression of the neural cell adhesion NCAM in endocrine cells of the ovary [PDF]

open access: yes, 1991
In the adult mammalian ovary morphogenesis and differentiation processes are under hormonal control and, thus, occur in a highly regulated way during the sexual cycle.
Gratzl, Manfred   +2 more
core   +1 more source

Single-cell reconstruction of follicular remodeling in the human adult ovary

open access: yesNature Communications, 2019
The ovary is perhaps the most dynamic organ in the human body, only rivaled by the uterus. The molecular mechanisms that regulate follicular growth and regression, ensuring ovarian tissue homeostasis, remain elusive.
X. Fan   +12 more
semanticscholar   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Annual fecundity, batch fecundity, and oocyte atresia of Atka mackerel (Pleurogrammus monopterygius) in Alaskan waters [PDF]

open access: yes, 2007
Annual potential fecundity, batch fecundity, and oocyte atresia were estimated for Atka mackerel (Pleurogrammus monopterygius) collected in Alaskan waters during 1993−94.
Gunderson, Donald R.   +2 more
core  

Structure of the ovaries of the Nimba otter shrew, Micropotamogale lamottei, and the Madagascar hedgehog tenrec, Echinops telfairi [PDF]

open access: yes, 2005
The otter shrews are members of the subfamily Potamogalinae within the family Tenrecidae. No description of the ovaries of any member of this subfamily has been published previously.
A.C. Enders   +18 more
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Helminth fauna of Mt. Ontake. Part 2. Trematoda and Cestoda [PDF]

open access: yes, 1954
I. Trematodes of mammals 1. Brachylaemus tokudai n. sp. 2. Acanthatrium ovatum Yamaguti, 1939 II. Cestodes of frogs 3. Baerietta montana n. sp. 4. Baerietta claviformis n. sp. III. Cestodes of· birds 5. Choanotaenia barbara Meggitt, 1926 IV.
Yamaguti, Satyu
core   +1 more source

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