Results 61 to 70 of about 893,568 (343)

Characteristics of polycystic ovary syndrome throughout life

Therapeutic Advances in Reproductive Health, 2020
Polycystic ovary syndrome is the most common endocrine disorder in women of reproductive age. It is a complex disease in which genetic, endocrine, environmental, and behavioral factors are intertwined, giving rise to a heterogeneous phenotype with ...
Y. Louwers, J. Laven
semanticscholar   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Association between circulating adiponectin levels and polycystic ovarian syndrome [PDF]

, 2014
Background: Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to insulin resistance (
Khan, Naveed Ali, Mirza, Saeed Mirza, Qureshi, Masood Anwar, Shafique, Kashif, Shaikh, Abdul Rauf   +4 more
core   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

The impact of female obesity on the outcome of fertility treatment [PDF]

, 2010
Peer reviewedPublisher ...
Abha Maheshwari, Ayyad, Balen, Balen, Bellver, Bellver, Bellver, Bergh, Brannian, Clark, Diamanti-Kandarakis, Dodson, Ehrmann, Gil-Campos, Hamilton-Fairley, Hollmann, Hossain, Huber-Buchholz, Imani, Imani, Jungheim, Kiddy, Koloszar, Law, Li, Maheshwari, Metwally, Metwally, Metwally, Moran, Moschos, Mulders, Nohr, Ogden, Orvieto, Palomba, Panidis, Pasquali, Prentice, Rich-Edwards, Shilpi Pandey, Siladitya Bhattacharya, Suruchi Pandey, Tang, The, Tsagareli, Van, Wadden, Wang, Wattanakumtornkul, Wise, Zaadstra, Zachariah, Zhang   +53 more
core   +3 more sources

Obesity and Polycystic Ovary Syndrome: Implications for Pathogenesis and Novel Management Strategies

Clinical Medicine Insights: Reproductive Health, 2019
Polycystic ovary syndrome (PCOS) is a common female condition typified by reproductive, hyperandrogenic, and metabolic features. Polycystic ovary syndrome is a genetic condition, exacerbated by obesity.
T. Barber, Petra Hanson, M. Weickert, S. Franks   +3 more
semanticscholar   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Metastatic gallbladder carcinoma presenting as an ovarian mass

Autopsy and Case Reports, 2021
Metastatic gallbladder carcinoma to the ovaries is occasional but a recognized entity. It can mimic, clinical and morphologically, a primary ovarian tumor, challenging the diagnosis.
Nidhin Rehman, Harish Sadashiva, Manoj Gopal Madakshira, Deep Kumar Raman   +3 more
doaj  

Histopathological Study of Ovarian Lesions in a Tertiary Care Centre in Rural Maharashtra [PDF]

Walawalkar International Medical Journal, 2020
Background and Introduction: Ovaries are commonest site of neoplastic and non neoplastic pathology presenting at any age from childhood to postmenopause; can be asymptomatic for long or manifest acutely and are common prevalent causes of hospital ...
Vaishali S Bhonsle1, Ruchita Palkar2, Shilpa Kamble3 and Vijay D. Dombale4
doaj  

Rodent Models of Polycystic Ovary Syndrome [PDF]

, 2013
Rodents are clearly valuable models for assessing disruption of fertility. The effects of different steroid treatments at different stages of reproductive life through from fetal to adult have been assessed for effects on fertility, ovarian morphology ...
Duncan, Colin, McNeilly, Alan S
core   +1 more source