Results 51 to 60 of about 3,255,424 (314)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
EnergiesProtecting AC microgrids (MGs) is a challenging task due to their dual operating modes—grid-connected and islanded—which cause sudden variations in fault currents. Traditional protection methods may no longer ensure network security.
León F. Serna-Montoya +3 more
doaj +1 more source
Optimization of grounding resistance in multitrain DC subway system based on MOEA/D‐DE
IET Intelligent Transport Systems, 2023 Currently, in multitrain DC subway system, abnormal increase of rail potential (RP) and stray current (SC) has seriously threatened the safe operation of the system.
Na Liu +7 more
doaj +1 more source
Zhejiang dianli, 2023 There is a difficulty in setting the coordination of over-current protection in the distribution network with distributed power sources and widely laying optical fiber for differential protection in the distribution network， the study on engineering ...
CHEN Yongkui, LI Hongmei, ZHU Jihong
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Design of a new type of protection circuit of mine-used intrinsic safety power supply
Gong-kuang zidonghua, 2013 The paper put forward a design scheme of a new type of protection circuit of mine-used intrinsic safety power supply with LM339 comparator and MAX4080SASA current detection chip based on the analysis of advantages and disadvantages of traditional ...
ZHOU Xue-feng
doaj
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Impact of Creditor Protection on Stock Prices in the Presence of Credit Crunches [PDF]
Data show that better creditor protection is correlated across countries with lower average stock market volatility. Moreover, countries with better creditor protection seem to have suffered lower decline in their stock market indexes during the current ...
Assaf Razin, Galina Hale, Hui Tong
core +3 more sources