Results 71 to 80 of about 3,276,165 (313)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Analisis Koordinasi Over Current Relay Dan Recloser Pada Sistem Distribusi 20kv Penyulang Palur12 Menggunakan Etap 12.6 [PDF]
, 2016 Short circuit interruption that often occur at the distribution system 20KV can cause distruption of the distribution of electrical energy to the consumer.
, Umar,ST.MT., Kurniawan Saputro, Azanto
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
High Speed Operation of Fuel Injectors with Over Current Protection
The Transactions of The Korean Institute of Electrical Engineers, 2011 High speed drive method for a fuel injector cleaner with current control is presented in this paper. The fuel injector cleaner is used for cleaning the fuel injectors in vehicles when it is clogged with deposit and rust. The fuel injector cleaner cleans the fuel injector by turning on and off the fuel injector rapidly.
Hyong-Yeol Yang, Eui-Suk Suh
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Political Economy of Declining Industries: Senescent Industry Collapse Revisited [PDF]
One of the most robust empirical regularities in the political economy of trade is the persistence of protection. This paper explains persistent protection in terms of the interaction between industry adjustment, lobbying, and the political response ...
S. Lael Brainard, Thierry Verdier
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A New Gate Driver for IGBT Devices with Multi-protections
机车电传动, 2015 The process of IGBT switching was analyzed, and then a new gate driver with multi-protections was designed. The contractive researches between new gate driver and common gate driver and researches on module short circuit were also done.
XIE Shunmeng +5 more
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