Results 81 to 90 of about 3,276,165 (313)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

1.7 kV IGBT Driver Based on Electromagnetism Isolation

open access: yesKongzhi Yu Xinxi Jishu, 2015
The basic characteristics of IGBT driver were analyzed and an IGBT driver based on electromagnetism isolation was designed. Chopping and short-circuit test researches on the driver were executed.
XIE Shunmeng   +4 more
doaj  

The Impact of Creditor Protection on Stock Prices in the Presence of Credit Crunches [PDF]

open access: yes
Data show that better creditor protection is correlated across countries with lower average stock market volatility. Moreover, countries with better creditor protection seem to have suffered lower decline in their stock market indexes during the current ...
Assaf Razin, Galina Hale, Hui Tong
core  

Differential Protection of a Three-Phase Power Transformer Using Hall Effect Current Transducer [PDF]

open access: yes, 2002
In a power system, transformers and other electrical equipment need to be protected not only from short circuit, but also from abnormal operating conditions, such as over loading, and differential fault protection.
Fathollahi Fard, Ali Asghar
core  

The role of regulatory mechanisms for control of plant diseases and food security — case studies from potato production in Britain [PDF]

open access: yes, 2010
Being aware of the potentially devastating impacts of plant diseases on food security, governments have designed and employ plant health legislation to prevent or inhibit the worst impacts.
Dehnen-Schmutz, Katharina   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Study on the Influence of Pulse Current Cathodic Protection Parameters of Oil Well Casing

open access: yesAdvances in Materials Science and Engineering, 2019
Pulse current cathodic protection had obvious advantages over traditional DC cathodic protection, but when square-wave pulse current was used for cathodic protection of oil well casing, the influence of pulse protection parameters on potential ...
Xiang-qian Xu, Hao-bin Zhou
doaj   +1 more source

Perancangan Rele Arus Lebih Dengan Karakteristik Invers Berbasis Mikrokontroler Atmega 8535

open access: yesJurnal Nasional Teknik Elektro, 2012
Untuk melindungi peralatan listrik dari kerusakan akibat gangguan hubung singkat atau short circuit  penyebab masalah yang harus diaman diperlukan suatu alat pengaman arus lebih (over current protection atau over current relay (OCR)).
Cahayahati ., Mirza Zoni Zoni
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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