Results 131 to 140 of about 10,510,063 (301)
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Multiple side-bands are generated from a single laser diode with the aid of optical carrier suppression, which facilitates the transmission of reduced-rate parallel streams mapped to the side-bands. As a benefit, all the signal processing tasks including
Hanzo, Lajos, Ghafoor, Salman
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Classical and Bayesian estimation of discrete poisson Agu-Eghwerido distribution with applications
This study presents a novel single-parameter counting model that merges the Poisson distribution with the Agu-Eghwerido distribution. The newly developed model is referred to as the ''Poisson Agu-Eghwerido Distribution.'' We investigate major ...
Osama Abdulaziz Alamri
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
A compound Poisson-Sujit framework for over-dispersed radiation monitoring data
This paper proposes a novel one-parameter discrete probability model, termed the Poisson–Sujit (PSJT) model, developed by compounding the classical Poisson distribution with the recently introduced Sujit (SJT) model.
Tabassum Naz Sindhu +5 more
doaj +1 more source
Inverse scattering designs of dispersion-engineered single-mode planar waveguides
We use an inverse-scattering (IS) approach to design single-mode waveguides with controlled linear and higher-order dispersion. The technique is based on a numerical solution to the Gelfand-Levitan-Marchenko integral equation, for the inversion of ...
Poletti, F. +5 more
core +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
This paper proposes the Poisson–Emrem (PEm) distribution, a new one-parameter discrete probability model obtained by compounding the Poisson and Emrem distributions.
Tabassum Naz Sindhu +4 more
doaj +1 more source

